关键词: breast cancer carbon ion particle photon proton radiotherapy

来  源:   DOI:10.3389/fonc.2023.1107703   PDF(Pubmed)

Abstract:
Breast cancer is the most common malignant tumor in female patients. Along with surgery, radiotherapy is one of the most commonly prescribed treatments for breast cancer. Over the past few decades, breast cancer radiotherapy technology has significantly improved. Nevertheless, related posttherapy complications should not be overlooked. Common complications include dose-related coronary toxicity, radiation pneumonia, and the risk of second primary cancer of the contralateral breast. Particle radiotherapy with protons or carbon ions is widely attracting interest as a potential competitor to conventional photon radiotherapy because of its superior physical and biological characteristics. This article summarizes the results of clinical research on proton and carbon-ion radiotherapy for treating breast cancer.
摘要:
乳腺癌是女性患者中最常见的恶性肿瘤。除了手术,放疗是乳腺癌最常用的治疗方法之一。在过去的几十年里,乳腺癌放疗技术有了明显的提高。然而,相关的治疗后并发症不容忽视。常见的并发症包括剂量相关的冠状动脉毒性,放射性肺炎,和对侧乳腺第二原发癌的风险。具有质子或碳离子的粒子放射疗法由于其优越的物理和生物学特性,作为常规光子放射疗法的潜在竞争者而受到广泛关注。本文总结了质子和碳离子放射治疗乳腺癌的临床研究结果。
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