METHODS: This study followed 713 patients who were randomly divided into two groups: a group that did not receive non-steroidal anti-inflammatory drugs (N-NSAIDs) consisting of 394 patients, and a group that received non-steroidal anti-inflammatory drugs (NSAIDs) comprising 319 patients. The study spanned a duration of 5 years (2018-2022), with patients being followed and evaluated for up to 6 months after the surgery.
RESULTS: It was observed that, from a therapeutic standpoint, the use of injectable treatments decreased. Significantly better differences were recorded in the N-NSAIDs group regarding return to pre-osteoarthritis activities at 6 months and reduced or absent night pain at 3 months (p<0.05).
CONCLUSIONS: Statistically significant improvements were observed in the N-NSAIDs group concerning the ability to resume pre-osteoarthritis activities within 6 months, as well as a reduction or absence of nighttime pain within 3 months.
方法:这项研究追踪了713名患者,他们被随机分为两组:一组没有接受非甾体抗炎药(N-NSAIDs)的394名患者,和一组接受非甾体类抗炎药(NSAIDs)的组,包括319名患者。该研究历时5年(2018-2022年),在手术后6个月内对患者进行随访和评估。
结果:观察到,从治疗的角度来看,注射治疗的使用减少。在N-NSAIDs组中,在6个月时恢复到骨关节炎前的活动以及在3个月时减轻或不存在夜间疼痛方面,差异显着(p<0.05)。
结论:在6个月内恢复骨关节炎前活动的能力方面,在N-NSAIDs组中观察到统计学上的显着改善,以及3个月内夜间疼痛的减轻或不存在。