Abstract:
Platelet-rich plasma (PRP), a blood-based product containing platelets and growth factors, is being utilized to treat numerous non-hemostatic disorders. Studies have explored the use of PRP to provide rapid repair, healing, and recovery from various injuries; some studies mentioned the effectiveness of PRP as compared with other forms of treatment like the use of hyaluronic acid. Commercially available PRP systems are available now, and each varies from one another depending on how it is prepared, thus causing variations in platelet concentration and growth factor content. These variations also implicated different therapeutic applications.
The paper reviews the various applications of PRP, including factors to consider before using PRP therapy, and provides an extensive list of PRP applications.
The administration of PRP as a standalone treatment or as a co-therapy results in observed positive outcomes. However, there is a lack of standardization for PRP preparation, increasing the risks for heterogeneity and bias amongst results.
The use of PRP is indeed an option for regenerative therapy, but more research is needed before it can fully be recommended as a primary treatment modality.
摘要:
背景:富血小板血浆(PRP),含有血小板和生长因子的血液产品,用于治疗许多非止血疾病。研究已经探索了使用PRP来提供快速修复,愈合,和从各种损伤中恢复;一些研究提到与使用透明质酸等其他形式的治疗相比,PRP的有效性。商用PRP系统现在可用,每个人都各不相同,这取决于它是如何准备的,从而引起血小板浓度和生长因子含量的变化。这些变化还涉及不同的治疗应用。
方法:本文回顾了PRP的各种应用,包括使用PRP治疗前要考虑的因素,并提供了广泛的PRP应用程序列表。
结果:将PRP作为独立治疗或联合治疗给药可观察到阳性结果。然而,PRP制备缺乏标准化,增加结果中异质性和偏见的风险。
结论:使用PRP确实是再生治疗的一种选择,但在完全将其推荐为主要治疗方式之前,还需要更多的研究。