PDF(Pubmed)
Abstract：
BACKGROUND: Mediastinal Liposarcoma (ML) is an exceedingly rare neoplasm, accounting for less than 1% of all liposarcomas. Surgical resection is the most effective therapeutic modality, while adjuvant radiation therapy may be recommended for unresectable tumors.
METHODS: This case report presents a rare case of a 52-year-old Syrian male patient with well-differentiated mediastinal liposarcoma (ML) who presented with exertional dyspnea, cough, and weight loss. Imaging studies revealed a large tumor causing extrinsic compression on the right lung, as well as compression of the heart and great vessels. CT-guided biopsy confirmed a diagnosis of well-differentiated liposarcoma, and the patient underwent surgical resection. The patient had a rapid postoperative recovery and was discharged on the fourth day post-operation, displaying an excellent postoperative status. The patient was followed up for 3 months postoperatively with no recurrence.
CONCLUSIONS: This report highlights the significance of incorporating ML into the differential diagnosis of mediastinal masses, particularly in individuals presenting with exertional dyspnea and weight loss. Furthermore, this report provides a comprehensive review of previously reported cases of ML in the medical literature.
METHODS: This case report presents a rare case of a 52-year-old Syrian male patient with well-differentiated mediastinal liposarcoma (ML) who presented with exertional dyspnea, cough, and weight loss. Imaging studies revealed a large tumor causing extrinsic compression on the right lung, as well as compression of the heart and great vessels. CT-guided biopsy confirmed a diagnosis of well-differentiated liposarcoma, and the patient underwent surgical resection. The patient had a rapid postoperative recovery and was discharged on the fourth day post-operation, displaying an excellent postoperative status. The patient was followed up for 3 months postoperatively with no recurrence.
CONCLUSIONS: This report highlights the significance of incorporating ML into the differential diagnosis of mediastinal masses, particularly in individuals presenting with exertional dyspnea and weight loss. Furthermore, this report provides a comprehensive review of previously reported cases of ML in the medical literature.
摘要：
背景：纵隔脂肪肉瘤（ML）是一种极为罕见的肿瘤，占所有脂肪肉瘤的不到1%。手术切除是最有效的治疗方法,而对于不可切除的肿瘤，可能建议进行辅助放射治疗。
方法：本病例报告介绍了一例罕见病例，一例52岁的叙利亚男性患者，患有高分化纵隔脂肪肉瘤（ML），表现为劳力性呼吸困难，咳嗽,和减肥。影像学检查显示，一个大肿瘤导致右肺外部压迫，以及心脏和大血管的压缩。CT引导活检证实了高分化脂肪肉瘤的诊断，患者接受了手术切除。患者术后恢复较快,术后第四天出院,表现出良好的术后状态。术后随访3个月，无复发。
结论：本报告强调了将ML纳入纵隔肿块鉴别诊断的重要性，特别是在表现为劳力性呼吸困难和体重减轻的个体中。此外，本报告对医学文献中以前报道的ML病例进行了全面回顾.
方法：本病例报告介绍了一例罕见病例，一例52岁的叙利亚男性患者，患有高分化纵隔脂肪肉瘤（ML），表现为劳力性呼吸困难，咳嗽,和减肥。影像学检查显示，一个大肿瘤导致右肺外部压迫，以及心脏和大血管的压缩。CT引导活检证实了高分化脂肪肉瘤的诊断，患者接受了手术切除。患者术后恢复较快,术后第四天出院,表现出良好的术后状态。术后随访3个月，无复发。
结论：本报告强调了将ML纳入纵隔肿块鉴别诊断的重要性，特别是在表现为劳力性呼吸困难和体重减轻的个体中。此外，本报告对医学文献中以前报道的ML病例进行了全面回顾.
