PDF(Pubmed)
Abstract：
Necrobiotic xanthogranuloma is a condition that was first identified in 1980 based on its characteristic histological identity, and it has been known since then as a dermatologic manifestation of an underlying systemic dysproteinemia. Intracranial manifestation is a rare presentation of this condition and has been reported only once in its more than 40 years of existence. Herein and to our knowledge, we report the second observation of an intracranial manifestation and, surprisingly, the first case without the expected dermatologic and systemic dysproteinemia associations. This case identifies an existing knowledge gap in our understanding of necrobiotic xanthogranuloma and emphasises the need for further research into understanding the presentation, comorbidities and management of this condition.
摘要：
坏死生物性黄色肉芽肿是一种疾病，在1980年首次发现，基于其特征性的组织学身份，从那时起，它就被认为是潜在的全身性蛋白异常血症的皮肤病表现。颅内表现是这种情况的罕见表现，在其存在40多年的时间里只有一次报道。在这里和我们的知识，我们报告了颅内表现的第二次观察，令人惊讶的是,第一例没有预期的皮肤病学和全身性蛋白异常血症关联。该案例确定了我们对坏死生物黄色肉芽肿的理解存在的知识差距，并强调需要进一步研究以理解该表现，合并症和这种情况的管理。
