PDF(Pubmed)
Abstract：
This study aimed to describe a rare case of gnathostomiasis in the vocal cord. A 54-year-old Chinese woman living in Korea visited with a chief complaint of voice change at the outpatient department of otorhinolaryngology in Hallym Sacred Heart Hospital, Hallym University on August 2, 2021. She had eaten raw conger a few weeks before the voice change developed, but her medical history and physical examinations demonstrated neither gastrointestinal symptoms nor other health problems. A round and red cystic lesion, recognized in the anterior part of the right vocal cord, was removed using forceps and scissors through laryngeal microsurgery. The histopathological specimen of the cyst revealed 3 cross-sections of a nematode larva in the lumen of the cyst wall composed of inflammatory cells and fibrotic tissues. They differ in diameter, from 190 μm to 235 μm. They showed characteristic cuticular layers with tegumental spines, somatic muscle layers, and gastrointestinal tracts such as the esophagus and intestine. Notably, intestinal sections consisted of 27-28 lining cells containing 0-4 nuclei per cell. We tentatively identified the nematode larva recovered from the vocal cord cystic lesion as the third-stage larva of Gnathostoma, probably G. nipponicum or G. hispidum, based on the sectional morphologies.
摘要：
这项研究旨在描述一种罕见的声带颌骨病。一名居住在韩国的54岁中国妇女在Hallym圣心医院耳鼻咽喉科门诊就诊，主要抱怨声音改变，哈勒姆大学2021年8月2日。她在声音变化发生前几周吃了生的conger，但是她的病史和体格检查既没有胃肠道症状也没有其他健康问题。圆形红色囊性病变，在右声带的前部识别，通过喉部显微手术使用镊子和剪刀移除。囊肿的组织病理学标本显示，囊壁内腔中有3个线虫幼虫的横截面，由炎性细胞和纤维化组织组成。它们的直径不同，从190μm到235μm。他们表现出特征性的角质层，带有外皮棘，躯体肌肉层，和胃肠道，如食道和肠。值得注意的是,肠道切片由27-28个衬里细胞组成，每个细胞含有0-4个细胞核。我们初步确定了从声带囊性病变中恢复的线虫幼虫为Gnathostoma的第三阶段幼虫，可能是日本龙舌兰，也可能是Hispidum,基于截面形态。
