关键词: 3D reconstruction CT Pierre Robin sequence Treacher Collins syndrome mandible measurement

来  源:   DOI:10.3389/fped.2023.1172909   PDF(Pubmed)

Abstract:
UNASSIGNED: We aimed to measure the related indicators of the neonatal mandible in East China. This provides basic data for the study of the mandible position and morphology of normal newborns and can also provide data support for the diagnosis, evaluation, and treatment of the Pierre Robin sequence.
UNASSIGNED: First, we collected the CT data of normal neonates at the Nanjing Children\'s Hospital Affiliated with Nanjing Medical University between January 2013 and January 2019. The data included the maxilla and mandible, and neonates had no craniomaxillofacial-related malformation. We exported the data in DICOM format. In the second step, we imported the data into MIMICS 21.0 to reconstruct the data into a 3D model, and then we used the model to measure the different measurement items. Specific measurement items were as follows: ① Measurement of the angle α: We imported the CT data of the neonate into the software and reconstructed a 3D model. We observed the 3D model to find the left and right gonions (LGo and RGo) and the Menton (Me) and used the angle measurement tool of the software to appoint Me as the apex, and we connected the points LGo, Me, and RGo as angle α. ② Measurement of the distance between the left and right gonions: The distance measurement tool of the software was used to measure the distance between the bilateral gonions as a. ③ Measurement of the distance from the Me to the line between LGo and RGo: The LGo and RGo were connected as a line on the 3D model, then the distance between Me and the line was measured as b. ④ Measurement of the distance between the upper and lower jaw: The median sagittal view was found and the distance c between the foremost point of the upper jaw and the foremost point of the lower jaw was measured. We imported the measurement results into the SPSS software for statistical analysis.
UNASSIGNED: Specific measurement results: ① Angle α: 86.34 ± 8.58°. ② Distance a: 63.63 ± 6.83 mm. ③ Distance b: 31.99 ± 3.70 mm. ④ Distance c: 2.28 ± 1.04 mm. Among all the above indicators, there was no statistical difference between gender.
UNASSIGNED: In this study, 132 neonates were initially screened, of which 117 met the inclusion criteria and were finally included. There were 69 male and 48 female neonates. The indicators α, a, b, and c showed no statistical differences between male and female neonates; therefore, we combined the results to obtain the normal reference value: angle α: 86.34 ± 8.58°; distance a: 63.63 ± 6.83 mm; distance b: 31.99 ± 3.70 mm; distance c: 2.28 ± 1.04 mm.
摘要:
我们旨在测量华东地区新生儿下颌骨的相关指标。这为正常新生儿下颌骨位置和形态的研究提供了基础数据,也为诊断提供了数据支持,评估,和皮埃尔·罗宾序列的处理。
首先,收集2013年1月至2019年1月南京医科大学附属南京儿童医院正常新生儿的CT资料。数据包括上颌骨和下颌骨,新生儿无颅颌面相关畸形。我们以DICOM格式导出数据。第二步,我们将数据导入MIMICS21.0,以将数据重建为3D模型,然后我们使用该模型来测量不同的测量项目。具体测量项目如下:①角度α的测量:我们将新生儿的CT数据导入软件并重建三维模型。我们观察了3D模型,找到了左右角(LGo和RGo)和Menton(Me),并使用软件的角度测量工具指定Me为顶点,我们连接了LGo点,我,和RGo为角度α。②左右角之间的距离测量:使用软件的距离测量工具测量双侧角之间的距离为a。③测量Me到LGo和RGo之间的距离:LGo和RGo在3D模型上连接为一条线,然后将Me与线之间的距离测量为b。④上颌和下颌之间距离的测量:找到正中矢状面视图,并测量上颌最前点与下颌最前点之间的距离c。将测量结果导入SPSS软件进行统计分析。
具体测量结果:①角度α:86.34±8.58°。②距离a:63.63±6.83mm。③距离b:31.99±3.70mm。④距离c:2.28±1.04mm。在上述所有指标中,性别差异无统计学意义。
在这项研究中,最初对132名新生儿进行了筛查,其中117人符合纳入标准,最终被纳入。有69名男性和48名女性新生儿。指标α,a,B,和c显示男性和女性新生儿之间没有统计学差异;因此,我们将结果合并以获得正常参考值:角度α:86.34±8.58°;距离a:63.63±6.83mm;距离b:31.99±3.70mm;距离c:2.28±1.04mm。
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