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Abstract：
Introduction The aim of the present study was to describe our institution\'s nine years of experience in the endoscopic endonasal management of cerebrospinal fluid (CSF) rhinorrhea and to discuss the causes, sites, and outcomes. Methodology The medical records of patients diagnosed with CSF rhinorrhea in King Abdulaziz Medical City-Jeddah (KAMC-J) between 2014 and 2023 were retrospectively reviewed, and all relevant information including body mass index, medical and surgical history, and postoperative outcomes were obtained. Results A total of 20 cases were included in the present study, sixteen (80%) of which were females and four (20%) were males. The mean age of participants was 42.59±13.9 years. Nine cases (45%) were spontaneous CSF rhinorrhea and 11 (55%) were traumatic; within the traumatic group, six cases (54%) were iatrogenic either following previous neurosurgery or functional endoscopic sinus surgery, while the remaining five cases were related to motor vehicle accidents. The mean body mass index for the spontaneous CSF leak was 32 Kg/m2, and 33 Kg/m2 for the traumatic leaks, no statistically significant difference was noted. The cribriform plate was the most common site of leakage (65%). A multilayer surgical technique using facia lata graft with nasoseptal flap was the most common choice for reconstruction with a first-attempt success rate approximating 90%. A recurrence was observed in two patients only. No major complications were reported. The average length of stay was nine days. Conclusion The endoscopic endonasal repair of CSF leak is a safe and reliable procedure and is associated with high success rates and low risk of complications. Therefore, it should be preferred as a first-line treatment for CSF rhinorrhea.
摘要：
介绍本研究的目的是描述我们机构在鼻内镜治疗脑脊液（CSF）鼻漏方面的九年经验，并讨论原因，网站,和结果。方法回顾性分析2014年至2023年在阿卜杜勒阿齐兹国王医疗城-吉达（KAMC-J）诊断为CSF鼻漏的患者的病历，以及所有相关信息，包括体重指数，病史和手术史，并获得了术后结局。结果本研究共纳入20例,其中16名（80％）为女性，4名（20％）为男性。参与者的平均年龄为42.59±13.9岁。9例(45%)为自发性脑脊液鼻漏，11例(55%)为创伤性；在创伤性组中，6例（54％）是医源性的，无论是在以前的神经外科手术或功能性内窥镜鼻窦手术后，其余五宗案件与机动车事故有关。自发性脑脊液渗漏的平均体重指数为32Kg/m2，创伤性渗漏的平均体重指数为33Kg/m2。没有发现统计学上的显著差异.筛板是最常见的泄漏部位(65%)。使用带有鼻中隔皮瓣的面膜移植的多层手术技术是重建的最常见选择，首次尝试成功率约为90％。仅在两名患者中观察到复发。无重大并发症报告。平均逗留时间为9天。结论鼻内镜下脑脊液漏修补术是一种安全可靠的手术，成功率高，并发症风险低。因此,应优先作为CSF鼻漏的一线治疗。
