Abstract：
Benign cysts of the thoracic cavity represent a group of rare lesions, the spectrum of which is expanding. Most of these are congenital in nature, secondary to abnormal development during embryogenesis while a smaller subset represents acquired lesions. We retrospectively reviewed the clinicopathologic features of 136 patients with thoracic cysts that were treated in our institution over a span of 20 years. The patients were 85 female and 51 male patients with an average age of 51 years. Eighty-four of the patients were asymptomatic (62%), the remainder mainly presented with chest pain, shortness of breath, or cough. Surgical resection was performed in 123 patients while 12 patients were treated with aspiration only and 1 underwent core biopsy. The cyst size ranged from 0.5 to 14.8 cm (mean, 4.4 cm); histologically, the lesions included 50 thymic cysts (28 multilocular; 22 unilocular), 37 bronchogenic cysts, 23 pleuropericardial cysts, 12 unclassified cysts, 6 Müllerian cysts, 5 enteric cysts, and 3 parathyroid cysts. Clinical follow-up revealed that 97 patients were alive and well 4 months to 37 years after initial diagnosis; 25 patients were lost to follow-up and 14 patients died of unrelated causes. The current study is one of the largest studies on the subject with emphasis on clinicopathologic characteristics. This series has a higher incidence of thymic cysts compared with prior publications and covers a wider spectrum of different histologic types than previously reported.
摘要：
胸腔良性囊肿代表一组罕见病变，其频谱正在扩大。其中大多数是先天性的，继发于胚胎发生过程中的异常发育，而较小的子集代表获得性病变。我们回顾性分析了在我们机构治疗了20年的136例胸囊肿患者的临床病理特征。其中女性85例,男性51例,平均年龄51岁。84例患者无症状(62%),其余主要表现为胸痛，呼吸急促,或者咳嗽。123例患者进行了手术切除，而12例仅接受抽吸治疗，1例接受了核心活检。囊肿大小0.5~14.8cm(平均,4.4厘米）；组织学上，病变包括50个胸腺囊肿（28个多房性；22个单眼），37个支气管囊肿，23个胸膜心包囊肿，12个未分类的囊肿，6穆勒囊肿，5个肠囊肿，和3个甲状旁腺囊肿。临床随访显示，最初诊断后4个月至37年，97例患者存活良好；25例患者失去随访，14例死于无关原因。目前的研究是对该主题的最大研究之一，重点是临床病理特征。与以前的出版物相比，该系列胸腺囊肿的发病率更高，并且涵盖了比以前报道的更广泛的不同组织学类型。
