Abstract：
Recently, synthetic cannabinoids (SCs) have emerged as new psychoactive substances (NPS) and have been frequently added to e-liquids, leading to their abuse. In order to detect SCs in e-liquids quickly and accurately, a thermal-assisted carbon fiber ionization mass spectrometry technique has been developed. The introduction of a heat source helps to reduce the matrix effects. The results indicate that the ratio of the slope of the matrix curve (e-liquids matrix) and the standard curve (methanol solution) for SCs analysis is close to 1, indicating a minimized matrix effect of this method. Furthermore, this method exhibits good quantitative ability when applied to real samples. It does not require sample pretreatment and is sensitive enough to directly quantify SCs in e-liquids. Our method is characterized by the ability to achieve rapid and direct quantitative analysis with minimized matrix effects. It provides a rapid and simple method for analyzing SCs in e-liquids.
摘要：
最近,合成大麻素（SC）已成为新的精神活性物质（NPS），并经常添加到电子液体，导致他们的虐待。为了快速准确地检测电子液体中的SCs,已开发出一种热辅助碳纤维电离质谱技术。热源的引入有助于减少基体效应。结果表明，SCs分析的基质曲线（电子液体基质）和标准曲线（甲醇溶液）的斜率之比接近1，表明该方法的基质效应最小化。此外，该方法应用于实际样品时具有良好的定量能力。它不需要样品预处理，并且足够灵敏，可以直接定量电子液体中的SC。我们的方法的特点是能够以最小化的基体效应实现快速直接的定量分析。它为分析电子液体中的SC提供了一种快速简单的方法。
