PDF(Pubmed)
Abstract：
UNASSIGNED: Magnetic resonance imaging (MRI) has been used to investigate eye shapes; however, reports involving children are scarce. This study aimed to determine ocular dimensions, and their correlations with refractive error, using three-dimensional MRI in emmetropic versus myopic children.
UNASSIGNED: Healthy school children aged < 10 years were invited to take part in this cross-sectional study. Refraction and best-corrected distance visual acuity (BCDVA) were determined using cycloplegic refraction and a logarithm of the minimum angle of resolution (logMAR) chart, respectively. All children underwent MRI using a 3-Tesla whole-body scanner. Quantitative eyeball measurements included the longitudinal axial length (LAL), horizontal width (HW), and vertical height (VH) along the cardinal axes. Correlation analysis was used to determine the association between the level of refractive error and the eyeball dimensions.
UNASSIGNED: A total of 70 eyes from 70 children (35 male, 35 female) with a mean (standard deviation [SD]) age of 8.38 (0.49) years were included and analyzed. Mean (SD) refraction (spherical equivalent, SEQ) and BCDVA were -2.55 (1.45) D and -0.01 (0.06) logMAR, respectively. Ocular dimensions were greater in myopes than in emmetropes (all P < 0.05), with no significant differences according to sex. Mean (SD) ocular dimensions were LAL 24.07 (0.91) mm, HW 23.41 (0.82) mm, and VH 23.70 (0.88) mm for myopes, and LAL 22.69 (0.55) mm, HW 22.65 (0.63) mm, and VH 22.94 (0.69) mm for emmetropes. Significant correlations were noted between SEQ and ocular dimensions, with a greater change in LAL (0.46 mm/D, P < 0.001) than in VH (0.27 mm/D, P < 0.001) and HW (0.22 mm/D, P = 0.001).
UNASSIGNED: Myopic eyeballs are larger than those with emmetropia. The eyeball elongates as myopia increases, with the greatest change in LAL, the least in HW, and an intermediate change in VH. These changes manifest in both sexes at a young age and low level of myopia. These data may serve as a reference for monitoring the development of refractive error in young Malaysian children of Chinese origin.
UNASSIGNED: Healthy school children aged < 10 years were invited to take part in this cross-sectional study. Refraction and best-corrected distance visual acuity (BCDVA) were determined using cycloplegic refraction and a logarithm of the minimum angle of resolution (logMAR) chart, respectively. All children underwent MRI using a 3-Tesla whole-body scanner. Quantitative eyeball measurements included the longitudinal axial length (LAL), horizontal width (HW), and vertical height (VH) along the cardinal axes. Correlation analysis was used to determine the association between the level of refractive error and the eyeball dimensions.
UNASSIGNED: A total of 70 eyes from 70 children (35 male, 35 female) with a mean (standard deviation [SD]) age of 8.38 (0.49) years were included and analyzed. Mean (SD) refraction (spherical equivalent, SEQ) and BCDVA were -2.55 (1.45) D and -0.01 (0.06) logMAR, respectively. Ocular dimensions were greater in myopes than in emmetropes (all P < 0.05), with no significant differences according to sex. Mean (SD) ocular dimensions were LAL 24.07 (0.91) mm, HW 23.41 (0.82) mm, and VH 23.70 (0.88) mm for myopes, and LAL 22.69 (0.55) mm, HW 22.65 (0.63) mm, and VH 22.94 (0.69) mm for emmetropes. Significant correlations were noted between SEQ and ocular dimensions, with a greater change in LAL (0.46 mm/D, P < 0.001) than in VH (0.27 mm/D, P < 0.001) and HW (0.22 mm/D, P = 0.001).
UNASSIGNED: Myopic eyeballs are larger than those with emmetropia. The eyeball elongates as myopia increases, with the greatest change in LAL, the least in HW, and an intermediate change in VH. These changes manifest in both sexes at a young age and low level of myopia. These data may serve as a reference for monitoring the development of refractive error in young Malaysian children of Chinese origin.
摘要：
■磁共振成像（MRI）已用于研究眼睛形状；但是，涉及儿童的报告很少。这项研究旨在确定眼睛的尺寸，以及它们与屈光不正的相关性，使用三维MRI在正视和近视儿童。
■10岁以下的健康儿童被邀请参加这项横断面研究。使用睫状肌麻痹屈光度和最小分辨率角（logMAR）图的对数确定屈光度和最佳校正的远距视力（BCDVA），分别。所有儿童都使用3特斯拉全身扫描仪进行了MRI检查。定量眼球测量包括纵向轴向长度(LAL)，水平宽度(HW),和沿基本轴的垂直高度（VH）。使用相关分析来确定屈光不正水平与眼球尺寸之间的关联。
■70名儿童（35名男性，35名女性），平均（标准偏差[SD]）年龄为8.38（0.49）岁。平均(SD)折射(球面等效，SEQ)和BCDVA为-2.55(1.45)D和-0.01(0.06)logMAR，分别。近视患者的眼部尺寸大于emmetrothes（均P<0.05）。根据性别没有显著差异。平均（SD）眼尺寸为LAL24.07（0.91）mm，硬件23.41(0.82)mm,和VH23.70（0.88）毫米的近视，LAL22.69(0.55)mm,硬件22.65(0.63)mm,和VH22.94（0.69）毫米的emmetrops。SEQ和眼睛尺寸之间存在显著相关性，LAL变化较大(0.46mm/D，P<0.001）比VH（0.27mm/D，P<0.001）和硬件（0.22mm/D，P=0.001)。
■近视的眼球比那些有正视眼的大。随着近视的增加，眼球伸长，随着LAL最大的变化，至少在HW，和VH的中间变化。这些变化在年轻和低水平近视的两性中都表现出来。这些数据可作为监测马来西亚华裔儿童屈光不正发展的参考。
■10岁以下的健康儿童被邀请参加这项横断面研究。使用睫状肌麻痹屈光度和最小分辨率角（logMAR）图的对数确定屈光度和最佳校正的远距视力（BCDVA），分别。所有儿童都使用3特斯拉全身扫描仪进行了MRI检查。定量眼球测量包括纵向轴向长度(LAL)，水平宽度(HW),和沿基本轴的垂直高度（VH）。使用相关分析来确定屈光不正水平与眼球尺寸之间的关联。
■70名儿童（35名男性，35名女性），平均（标准偏差[SD]）年龄为8.38（0.49）岁。平均(SD)折射(球面等效，SEQ)和BCDVA为-2.55(1.45)D和-0.01(0.06)logMAR，分别。近视患者的眼部尺寸大于emmetrothes（均P<0.05）。根据性别没有显著差异。平均（SD）眼尺寸为LAL24.07（0.91）mm，硬件23.41(0.82)mm,和VH23.70（0.88）毫米的近视，LAL22.69(0.55)mm,硬件22.65(0.63)mm,和VH22.94（0.69）毫米的emmetrops。SEQ和眼睛尺寸之间存在显著相关性，LAL变化较大(0.46mm/D，P<0.001）比VH（0.27mm/D，P<0.001）和硬件（0.22mm/D，P=0.001)。
■近视的眼球比那些有正视眼的大。随着近视的增加，眼球伸长，随着LAL最大的变化，至少在HW，和VH的中间变化。这些变化在年轻和低水平近视的两性中都表现出来。这些数据可作为监测马来西亚华裔儿童屈光不正发展的参考。
