Abstract：
Oral verrucous hyperplasia (OVH) refers to a whitish or pink elevated plaque or mass on the oral mucosa with either verrucous or papillary surface. Given its potential of malignant transformation, it is crucial to pursue aggressive treatment and close surveillance to the lesion. Herein, we present a case of a 43-year-old male patient with large area OVH on the left buccal mucosa who was successfully treated using diode laser ablation combined with 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT). After two sessions of treatment, the lesions regressed completely, and no recurrence was observed at the 18-month follow-up. Therefore, diode laser ablation combined with ALA-PDT may be an efficient and safe treatment modality for large area OVH.
摘要：
口腔疣状增生（OVH）是指口腔粘膜上的白色或粉红色隆起的斑块或肿块，具有疣状或乳头状表面。鉴于其恶性转化的潜力，对病灶进行积极治疗和密切监测是至关重要的.在这里，我们介绍了1例43岁的男性患者,在左侧颊黏膜上出现大面积OVH,该患者使用二极管激光消融联合5-氨基酮戊酸介导的光动力疗法(ALA-PDT)成功治疗.经过两次治疗，病变完全消退，随访18个月时无复发.因此,二极管激光消融结合ALA-PDT可能是大面积OVH的有效和安全的治疗方式。
