PDF(Pubmed)
Abstract：
The repercussions of coronavirus disease 2019 (COVID-19) have been devastating on a global scale. Long COVID, which affects patients for weeks or even months after their initial infection, is not limited to individuals with severe symptoms and can affect people of all ages. The condition can impact various physiological systems, leading to chronic health conditions and long-term disabilities that present significant challenges for healthcare systems worldwide. This review explores the link between long COVID and cardiovascular complications such as myocardial injury and myocarditis. It also highlights the prevalence of these complications and identifies risk factors for their development in long COVID patients. Myocardial injury occurs due to direct cellular damage and T-cell-mediated cytotoxicity resulting in elevated cardiac biomarkers. Diagnostic techniques like electrocardiogram, troponin level testing, and magnetic resonance imaging can help identify myocarditis, but endomyocardial biopsy is considered the gold-standard diagnostic technique. Guideline-directed medical therapy is recommended for COVID-19 myocarditis patients for better prognosis while being monitored under comprehensive care management approaches. Therefore, it\'s critical to develop effective screening techniques specifically for vulnerable populations while conducting further research that addresses the effects of long COVID on society\'s physical health.
摘要：
2019年冠状病毒病(COVID-19)的影响在全球范围内是毁灭性的。长COVID,在初次感染后影响患者数周甚至数月，不仅限于有严重症状的人，而且可以影响所有年龄段的人。这种情况会影响各种生理系统，导致慢性健康状况和长期残疾，这对全球医疗保健系统提出了重大挑战。这篇综述探讨了长COVID与心血管并发症如心肌损伤和心肌炎之间的联系。它还强调了这些并发症的患病率，并确定了长期COVID患者发生这些并发症的危险因素。心肌损伤是由于直接的细胞损伤和T细胞介导的细胞毒性导致心脏生物标志物升高而发生的。心电图等诊断技术,肌钙蛋白水平测试,磁共振成像可以帮助识别心肌炎，但心内膜活检被认为是金标准诊断技术.建议对COVID-19心肌炎患者进行指导的药物治疗，以改善预后，同时在综合护理管理方法下进行监测。因此,开发专门针对弱势人群的有效筛查技术至关重要，同时进行进一步的研究，以解决长期COVID对社会身体健康的影响。
