PDF(Pubmed)
Abstract：
Granulomatosis with polyangiitis is a rare disease with involvement of multiple organ system. It classically affects the upper respiratory tract, lower respiratory tract and kidneys. 90% of patients present with upper respiratory diseases like rhinosinusitis, nasal polyposis, nasal septal perforation, serous otitis media, impaired hearing and stridor due to subglottic stenosis. Disease manifests in two forms as limited disease i.e. without renal involvement and generalized disease i.e. with renal involvement. It needs to be differentiated from chronic granulomatous diseases like tuberculosis and delay in the treatment should be prevented. Here we present a case with disease limited to Nose and Paranasal sinuses.
摘要：
肉芽肿病伴多血管炎是一种罕见的多器官受累疾病。它通常影响上呼吸道，下呼吸道和肾脏。90%的患者患有鼻窦炎等上呼吸道疾病，鼻息肉病,鼻中隔穿孔,浆液性中耳炎,声门下狭窄引起的听力受损和喘鸣。疾病以两种形式表现为局限性疾病，即没有肾脏受累和广泛性疾病，即有肾脏受累。需要将其与结核病等慢性肉芽肿疾病区分开来，并应防止治疗延迟。在这里，我们提出了一个仅限于鼻和鼻旁窦的疾病病例。
