PDF(Pubmed)
Abstract：
In critical patients, generally, microorganisms originating from nasal cause Ventilator-Associated Pneumonia (VAP). This systematic review was aimed to identify the toothbrush U shape model usage, in potentially decrease the prevalence of ventilator-associated pneumonia among patients in intensive care units. Search strategy identified 15 potentially eligible articles, were 7 RCTs, 4 Meta-analysis, and 4 Observational studies. A total of 15 studies demonstrated the use of toothbrushing and chlorhexidine in mechanically ventilator patients in preventing VAP. Ten studies found positive association between toothbrushing and the use of chlorhexidine in preventing VAP. However, there were 5 studies that did not reveal an additional decrease of VAP incidence either of CHX and only toothbrushing or combination thereof. We cautiously assumed that toothbrushing and chlorhexidine might reduce VAP but the implementation of brushing should be taken into reconsideration in the terms of maintaining it.
摘要：
在危重患者中，一般来说,来自鼻腔的微生物引起呼吸机相关性肺炎（VAP）。本系统综述旨在确定牙刷U形模型的使用情况，有可能降低重症监护病房患者呼吸机相关性肺炎的患病率.搜索策略确定了15篇潜在符合条件的文章，有7个RCT，4元分析，4观察性研究。共有15项研究表明，在机械呼吸机患者中使用刷牙和氯己定预防VAP。十项研究发现刷牙与使用氯己定预防VAP之间存在正相关。然而,有5项研究未显示CHX和仅刷牙或其组合的VAP发生率进一步降低。我们谨慎地认为，刷牙和洗必泰可能会减少VAP，但在维持VAP方面，应重新考虑刷牙的实施。
