PDF(Pubmed)
Abstract：
Plant viruses are tiny pathogenic obligate parasites that cause significant damage to global crop production. They exploit and manipulate the cellular components of host plants to ensure their own survival. In response, plants activate multiple defense signaling pathways, such as gene silencing and plant hormone signaling, to hinder virus propagation. Growing evidence suggests that the regulation of protein homeostasis plays a vital role in the ongoing battle between plants and viruses. The ubiquitin-proteasome-degradation system (UPS) and autophagy, as two major protein-degradation pathways, are widely utilized by plants and viruses in their arms race. One the one hand, these pathways act as essential components of plant\'s antiviral defense system by facilitating the degradation of viral proteins; on the other hand, viruses exploit the UPS and autophagy to create a favorable intracellular environment for viral infection. This review aims to provide a comprehensive summary of the events involved in protein homeostasis regulation during viral infection in plants. Gaining knowledge in this area will enhance our understanding of the complex interplay between plants and viruses.
摘要：
植物病毒是微小的致病性专性寄生虫，对全球作物生产造成重大损害。他们利用和操纵宿主植物的细胞成分来确保自己的生存。作为回应,植物激活多种防御信号通路，如基因沉默和植物激素信号，阻碍病毒传播。越来越多的证据表明，蛋白质稳态的调节在植物和病毒之间的持续斗争中起着至关重要的作用。泛素-蛋白酶体降解系统（UPS）和自噬，作为两种主要的蛋白质降解途径，在军备竞赛中被植物和病毒广泛利用。一只手，这些途径作为植物抗病毒防御系统的重要组成部分，通过促进病毒蛋白的降解；另一方面，病毒利用UPS和自噬为病毒感染创造了有利的细胞内环境。这篇综述旨在全面总结植物病毒感染过程中蛋白质稳态调节的事件。获得这方面的知识将增强我们对植物和病毒之间复杂相互作用的理解。
