PDF(Pubmed)
Abstract：
Amniotic tissues and methylene blue (MB) provide the ability for neuroregeneration, and MB enables intraoperative neurostaining. We first combined the techniques to explore a neuroprotective effect on early functional outcomes in a retrospective proof-of-concept trial of 14 patients undergoing radical prostatectomy (RP). The patients were followed up at a median of 13 months, and the continence and potency rates were reported. Early recovery of continence was found after three months. No effect on potency was detected. The findings indicate the feasibility of this tissue-engineering strategy, and justify prospective comparative studies.
摘要：
羊膜组织和亚甲蓝（MB）提供神经再生的能力，和MB可以进行术中神经染色。我们首先在一项对14例接受根治性前列腺切除术（RP）的患者进行的回顾性概念验证试验中，将这些技术结合起来，以探索对早期功能结局的神经保护作用。患者中位随访13个月,报告了节制率和效能率。三个月后发现尿失禁的早期恢复。未检测到对效力的影响。研究结果表明这种组织工程策略的可行性，并证明前瞻性比较研究的合理性。
