PDF(Pubmed)
Abstract：
Photoacoustic tomography has emerged as a prominent medical imaging technique that leverages its hybrid nature to provide deep penetration, high resolution, and exceptional optical contrast with notable applications in early cancer detection, functional brain imaging, drug delivery monitoring, and guiding interventional procedures. Test phantoms are pivotal in accelerating technology development and commercialization, specifically in photoacoustic (PA) imaging, and can be optimized to achieve significant advancements in PA imaging capabilities.
The analysis of material properties, structural characteristics, and manufacturing methodologies of test phantoms from existing imaging technologies provides valuable insights into their applicability to PA imaging. This investigation enables a deeper understanding of how phantoms can be effectively employed in the context of PA imaging.
Three primary categories of test phantoms (simple, intermediate, and advanced) have been developed to differentiate complexity and manufacturing requirements. In addition, four sub-categories (tube/channel, block, test target, and naturally occurring phantoms) have been identified to encompass the structural variations within these categories, resulting in a comprehensive classification system for test phantoms.
Based on a thorough examination of literature and studies on phantoms in various imaging modalities, proposals have been put forth for the development of multiple PA-capable phantoms, encompassing considerations related to the material composition, structural design, and specific applications within each sub-category.
The advancement of novel and sophisticated test phantoms within each sub-category is poised to foster substantial progress in both the commercialization and development of PA imaging. Moreover, the continued refinement of test phantoms will enable the exploration of new applications and use cases for PA imaging.
The analysis of material properties, structural characteristics, and manufacturing methodologies of test phantoms from existing imaging technologies provides valuable insights into their applicability to PA imaging. This investigation enables a deeper understanding of how phantoms can be effectively employed in the context of PA imaging.
Three primary categories of test phantoms (simple, intermediate, and advanced) have been developed to differentiate complexity and manufacturing requirements. In addition, four sub-categories (tube/channel, block, test target, and naturally occurring phantoms) have been identified to encompass the structural variations within these categories, resulting in a comprehensive classification system for test phantoms.
Based on a thorough examination of literature and studies on phantoms in various imaging modalities, proposals have been put forth for the development of multiple PA-capable phantoms, encompassing considerations related to the material composition, structural design, and specific applications within each sub-category.
The advancement of novel and sophisticated test phantoms within each sub-category is poised to foster substantial progress in both the commercialization and development of PA imaging. Moreover, the continued refinement of test phantoms will enable the exploration of new applications and use cases for PA imaging.
摘要：
■光声层析成像技术已经成为一种突出的医学成像技术，利用其混合特性提供深度穿透，高分辨率,和卓越的光学对比，在早期癌症检测中具有显著的应用，脑功能成像，药物输送监测，并指导介入程序。测试体模在加速技术开发和商业化方面至关重要，特别是在光声(PA)成像中，并且可以进行优化，以实现PA成像功能的显着进步。
■材料性能分析，结构特征，现有成像技术的测试体模的制造方法为其对PA成像的适用性提供了有价值的见解。这项研究可以更深入地了解如何在PA成像的背景下有效地使用幻影。
■测试体模的三个主要类别(简单，中间,和先进)已经开发出来，以区分复杂性和制造要求。此外,四个子类别(管/通道，块,测试目标,和自然存在的幻影)已被确定为涵盖这些类别内的结构变化，从而形成了一个全面的测试体模分类系统。
■在对各种成像方式中的幻影的文献和研究的基础上，已经提出了开发多个具有PA能力的幻影的建议，包括与材料成分相关的考虑因素，结构设计,以及每个子类别中的特定应用程序。
■每个子类别中新颖和复杂的测试体模的进步有望促进PA成像的商业化和开发方面的实质性进展。此外，测试体模的持续改进将有助于探索PA成像的新应用和用例。
■材料性能分析，结构特征，现有成像技术的测试体模的制造方法为其对PA成像的适用性提供了有价值的见解。这项研究可以更深入地了解如何在PA成像的背景下有效地使用幻影。
■测试体模的三个主要类别(简单，中间,和先进)已经开发出来，以区分复杂性和制造要求。此外,四个子类别(管/通道，块,测试目标,和自然存在的幻影)已被确定为涵盖这些类别内的结构变化，从而形成了一个全面的测试体模分类系统。
■在对各种成像方式中的幻影的文献和研究的基础上，已经提出了开发多个具有PA能力的幻影的建议，包括与材料成分相关的考虑因素，结构设计,以及每个子类别中的特定应用程序。
■每个子类别中新颖和复杂的测试体模的进步有望促进PA成像的商业化和开发方面的实质性进展。此外，测试体模的持续改进将有助于探索PA成像的新应用和用例。
