PDF(Pubmed)
Abstract：
Chronic lower back pain (CLBP) affects 25% of U.S. adults and is associated with high costs due to physician visits and reduced productivity. Research shows that massage and yoga can be effective nonpharmacological treatments for CLBP, but the feasibility, scalability, individual treatment, and adverse-event heterogeneity of these treatments are unknown. The current study evaluated the feasibility and acceptability of a series of personalized (N-of-1) interventions for virtual delivery of massage and yoga or usual-care treatment for CLBP in 57 participants. We hypothesized that this study would provide valuable information about implementing a virtual, personalized platform for randomized controlled trials of personalized (N-of-1) interventions among individuals with CLBP. The study will do so by determining participants\' ratings of usability and satisfaction with the virtual, personalized intervention delivery system and, in the long term, identifying ways to integrate these personalized trials into patient care. Of the 57 participants enrolled, two withdrew from the study and were not eligible to receive the primary outcome assessment. Thirty-seven of the remaining 55 participants (67.3%) completed satisfaction surveys comprising the System Usability Scale (SUS) and items assessing satisfaction with the components of the personalized trial. Participants rated the usability of the personalized trial as excellent (average SUS score = 85.8), 95% were satisfied with the personalized trial overall, and 100% stated they would recommend the trial to others. These results suggest that personalized trials of massage and yoga are highly feasible and acceptable to participants with CLBP.
摘要：
慢性下腰痛（CLBP）影响了25％的美国成年人，并且由于就诊和生产力下降而导致的高成本。研究表明，按摩和瑜伽可以有效的非药物治疗CLBP，但可行性,可扩展性，个体化治疗,这些治疗的不良事件异质性未知。本研究评估了57名参与者的一系列个性化（N-of-1）干预措施的可行性和可接受性，用于虚拟提供按摩和瑜伽或CLBP的常规护理治疗。我们假设这项研究将提供有关实施虚拟，在CLBP患者中进行个性化（N-of-1）干预的随机对照试验的个性化平台。这项研究将通过确定参与者对可用性和满意度的评价来做到这一点，个性化干预递送系统和，从长远来看,确定将这些个性化试验整合到患者护理中的方法。在注册的57名参与者中，2人退出研究,不符合接受主要结局评估的条件.其余55名参与者中有37名(67.3%)完成了满意度调查，包括系统可用性量表(SUS)和评估对个性化试验组成部分满意度的项目。参与者将个性化试验的可用性评为优秀（平均SUS评分=85.8），95%的人对个性化试验总体上感到满意，100%的人说他们会向其他人推荐这个试验。这些结果表明，按摩和瑜伽的个性化试验对于CLBP参与者是高度可行和可接受的。
