Abstract：
Mucormycosis is a serious and invasive fungal infection caused by Mucorales fungi. This review article provides a concise overview of the pathogenesis, epidemiology, microbiology, and diagnosis of mucormycosis. The introduction section highlights the key microbiological properties of the pathogen and delves into the underlying mechanisms of mucormycosis pathogenesis, including the invasion and proliferation of the fungus within the host. The description of the disease section focuses on the epidemiology of mucormycosis, including its incidence, risk factors, and geographical distribution. It also explores the specific context of mucormycosis infection about COVID-19 and diabetes mellitus, highlighting the increased susceptibility observed in individuals with these conditions. A case study illustrates the clinical manifestations and challenges associated with mucormycosis, emphasizing the importance of early detection. Additionally, the review discusses the diagnosis of mucormycosis, emphasizing the significance of clinical assessment, radiological imaging, and microbiological tests for accurate and timely detection of the infection. Regarding treatment, the article covers the various therapeutic approaches, including antifungal therapy, surgical interventions, and management of underlying predisposing conditions. The limitations and challenges associated with treatment options are also addressed. This review aims to provide a comprehensive understanding of mucormycosis, equipping healthcare professionals with valuable insights into its pathogenesis, epidemiology, microbiology, and diagnostic strategies. By enhancing knowledge and awareness of this fungal infection, this review can improve patient outcomes through early diagnosis and appropriate management.
摘要：
毛霉菌病是由毛霉菌引起的严重的侵袭性真菌感染。这篇综述文章简要概述了其发病机制，流行病学,微生物学,和毛霉菌病的诊断。引言部分重点介绍了病原体的关键微生物学特性，并深入研究了毛霉菌病发病机理的潜在机制，包括真菌在宿主内的侵袭和增殖。疾病部分的描述侧重于毛霉菌病的流行病学，包括它的发病率，危险因素，和地理分布。它还探讨了关于COVID-19和糖尿病的毛霉菌病感染的具体情况，强调在患有这些疾病的个体中观察到的易感性增加。一个案例研究说明了与毛霉菌病相关的临床表现和挑战，强调早期检测的重要性。此外,这篇综述讨论了毛霉菌病的诊断，强调临床评估的重要性，放射成像，和微生物测试，以准确及时地检测感染。关于治疗,这篇文章涵盖了各种治疗方法，包括抗真菌治疗,手术干预，以及潜在易感条件的管理。还解决了与治疗选择相关的限制和挑战。这篇综述旨在提供一个全面的了解毛霉菌病,为医疗保健专业人员提供对其发病机理的宝贵见解，流行病学,微生物学,和诊断策略。通过增强对这种真菌感染的认识和认识，本综述可以通过早期诊断和适当的管理来改善患者的预后.
