Abstract：
UNASSIGNED: To assess the prevalence of diminished ovarian reserve (DOR) in Chinese women with follicular cysts and menstrual disorders and relationship to hormonal markers.
UNASSIGNED: 117 women with follicular cysts and menstrual disorders, aged 24 ∼ 53 (39.19 ± 6.61) years; measurements of height, weight, follicle-stimulating hormone (FSH), luteinizing hormone (LH), E2, progesterone (Po), prolactin (PRL), total testosterone, AMH, follicular cyst diameter, endometrial thickness. Three age groups were compared: 1) 21 ∼ 30 years, 2) 30 ∼ 40 years, 3) > 40 years.
UNASSIGNED: Total prevalence of DOR 86.3%, in the groups 50%, 81.6%, and 98.4%, in group-3 significantly higher than in group-1 and 2. 34.2% of the 117 patients complained of cessation of regular menstruations or amenorrhea, 65.8% of abnormal uterine bleeding. Follicular cysts disappeard in cycle-1 for 98 (83.8%) and in cycle-2 for 117 (100%) patients. AMH decreased with age, significantly different between the three groups. Total testosterone in group-1 and 2 was significantly higher than in group-3. In total AMH had a negative correlation with age and E2 (p < 0.01) and positive correlation with total testosterone (p < 0.05).
UNASSIGNED: Assessing ovarian reserve with follicular cysts and menstrual disorders is important because often pointing to DOR. The overall prevalence of DOR was high; even young women (<40 years) with follicular cysts and menstrual disorders had a low level of AMH. So AMH can be used as a marker to define DOR with higher sensitivity than other markers like FSH and E2. Primarily, these results only apply to Chinese women and should be confirmed in further studies.
UNASSIGNED: 117 women with follicular cysts and menstrual disorders, aged 24 ∼ 53 (39.19 ± 6.61) years; measurements of height, weight, follicle-stimulating hormone (FSH), luteinizing hormone (LH), E2, progesterone (Po), prolactin (PRL), total testosterone, AMH, follicular cyst diameter, endometrial thickness. Three age groups were compared: 1) 21 ∼ 30 years, 2) 30 ∼ 40 years, 3) > 40 years.
UNASSIGNED: Total prevalence of DOR 86.3%, in the groups 50%, 81.6%, and 98.4%, in group-3 significantly higher than in group-1 and 2. 34.2% of the 117 patients complained of cessation of regular menstruations or amenorrhea, 65.8% of abnormal uterine bleeding. Follicular cysts disappeard in cycle-1 for 98 (83.8%) and in cycle-2 for 117 (100%) patients. AMH decreased with age, significantly different between the three groups. Total testosterone in group-1 and 2 was significantly higher than in group-3. In total AMH had a negative correlation with age and E2 (p < 0.01) and positive correlation with total testosterone (p < 0.05).
UNASSIGNED: Assessing ovarian reserve with follicular cysts and menstrual disorders is important because often pointing to DOR. The overall prevalence of DOR was high; even young women (<40 years) with follicular cysts and menstrual disorders had a low level of AMH. So AMH can be used as a marker to define DOR with higher sensitivity than other markers like FSH and E2. Primarily, these results only apply to Chinese women and should be confirmed in further studies.
摘要：
■评估中国女性卵泡囊肿和月经失调的卵巢储备功能减退（DOR）的患病率及其与激素标志物的关系。
■117名患有卵泡囊肿和月经紊乱的女性，年龄24~53(39.19±6.61)岁；身高测量，体重,卵泡刺激素（FSH），黄体生成素(LH),E2，孕酮（Po），催乳素（PRL），总睾酮,AMH,卵泡囊肿直径，子宫内膜厚度。三个年龄组进行了比较：1)21~30岁，2)30~40年，3）>40年。
■DOR的总患病率为86.3%，在50%的组中，81.6%,98.4%,3组明显高于1组和2组。117例患者中有34.2％抱怨停止定期月经或闭经，异常子宫出血占65.8%。卵泡囊肿在第1周期消失了98例（83.8％），在第2周期消失了117例（100％）。AMH随年龄增长而下降,三组之间有显著差异。1组和2组的总睾酮显著高于3组。总AMH与年龄、E2呈负相关(p<0.01),与总睾酮呈正相关(p<0.05)。
■评估卵泡囊肿和月经失调的卵巢储备非常重要，因为经常指向DOR。DOR的总体患病率很高；即使患有卵泡囊肿和月经失调的年轻女性（<40岁）也具有低水平的AMH。因此AMH可以用作标记来定义DOR，其灵敏度高于FSH和E2等其他标记。首先,这些结果仅适用于中国女性，应在进一步的研究中得到证实。
■117名患有卵泡囊肿和月经紊乱的女性，年龄24~53(39.19±6.61)岁；身高测量，体重,卵泡刺激素（FSH），黄体生成素(LH),E2，孕酮（Po），催乳素（PRL），总睾酮,AMH,卵泡囊肿直径，子宫内膜厚度。三个年龄组进行了比较：1)21~30岁，2)30~40年，3）>40年。
■DOR的总患病率为86.3%，在50%的组中，81.6%,98.4%,3组明显高于1组和2组。117例患者中有34.2％抱怨停止定期月经或闭经，异常子宫出血占65.8%。卵泡囊肿在第1周期消失了98例（83.8％），在第2周期消失了117例（100％）。AMH随年龄增长而下降,三组之间有显著差异。1组和2组的总睾酮显著高于3组。总AMH与年龄、E2呈负相关(p<0.01),与总睾酮呈正相关(p<0.05)。
■评估卵泡囊肿和月经失调的卵巢储备非常重要，因为经常指向DOR。DOR的总体患病率很高；即使患有卵泡囊肿和月经失调的年轻女性（<40岁）也具有低水平的AMH。因此AMH可以用作标记来定义DOR，其灵敏度高于FSH和E2等其他标记。首先,这些结果仅适用于中国女性，应在进一步的研究中得到证实。
