Abstract：
Many studies have reported the role of hair follicles (HFs) in the wound healing response, and vice versa, the creation of superficial injuries may stimulate hair growth, which has encouraged new treatments for hair loss.
To review the phenomenon of wound-induced hair growth and the usefulness of therapeutic procedures based on skin wounding in androgenetic alopecia (AGA).
A literature search was conducted to review cases of localized hypertrichosis induced by wounds and the role of microneedling, fractional laser, and scalp threading as monotherapy for AGA.
Localized hypertrichosis has been extensively reported after bone fractures, burn injury, chronic venous ulcer, etc. Only 2 cases of wound-induced hair neogenesis in humans have been reported. As monotherapy for AGA, 1 of 3 studies of microneedling, 4 of 6 of fractional lasers, and 2 of 3 studies of scalp threading show good efficacy.
Certain types of wounds seem to stimulate localized hair growth in humans, but the underlying mechanism is unclear. Reports on wound-induced HF neogenesis in humans are anecdotal and questions remain as to whether this is a true phenomenon in humans. Further clinical studies are needed before recommending wound-induced hair growth procedures as therapies for AGA.
To review the phenomenon of wound-induced hair growth and the usefulness of therapeutic procedures based on skin wounding in androgenetic alopecia (AGA).
A literature search was conducted to review cases of localized hypertrichosis induced by wounds and the role of microneedling, fractional laser, and scalp threading as monotherapy for AGA.
Localized hypertrichosis has been extensively reported after bone fractures, burn injury, chronic venous ulcer, etc. Only 2 cases of wound-induced hair neogenesis in humans have been reported. As monotherapy for AGA, 1 of 3 studies of microneedling, 4 of 6 of fractional lasers, and 2 of 3 studies of scalp threading show good efficacy.
Certain types of wounds seem to stimulate localized hair growth in humans, but the underlying mechanism is unclear. Reports on wound-induced HF neogenesis in humans are anecdotal and questions remain as to whether this is a true phenomenon in humans. Further clinical studies are needed before recommending wound-induced hair growth procedures as therapies for AGA.
摘要：
背景：许多研究报道了毛囊（HFs）在伤口愈合反应中的作用，反之亦然,表面损伤的产生可能会刺激头发生长，这鼓励了脱发的新疗法。
目的：综述了雄激素性脱发（AGA）中伤口引起的毛发生长现象以及基于皮肤损伤的治疗方法的有效性。
方法：进行文献检索，以回顾由伤口引起的局部多毛症病例和微针的作用，点阵激光,和头皮穿线作为AGA的单一疗法。
结果：骨折后局部多毛症已被广泛报道，烧伤,慢性静脉性溃疡,等。仅报道了2例人类伤口诱导的毛发新生。作为AGA的单一疗法，微针的3项研究中的1项，6个分数激光器中的4个，3项头皮穿线研究中的2项显示出良好的疗效。
结论：某些类型的伤口似乎刺激人体局部毛发生长，但潜在的机制尚不清楚。关于人类中伤口诱导的HF新生的报道是轶事，并且关于这是否是人类中的真实现象的问题仍然存在。在推荐伤口诱导的毛发生长程序作为AGA的疗法之前,需要进一步的临床研究。
目的：综述了雄激素性脱发（AGA）中伤口引起的毛发生长现象以及基于皮肤损伤的治疗方法的有效性。
方法：进行文献检索，以回顾由伤口引起的局部多毛症病例和微针的作用，点阵激光,和头皮穿线作为AGA的单一疗法。
结果：骨折后局部多毛症已被广泛报道，烧伤,慢性静脉性溃疡,等。仅报道了2例人类伤口诱导的毛发新生。作为AGA的单一疗法，微针的3项研究中的1项，6个分数激光器中的4个，3项头皮穿线研究中的2项显示出良好的疗效。
结论：某些类型的伤口似乎刺激人体局部毛发生长，但潜在的机制尚不清楚。关于人类中伤口诱导的HF新生的报道是轶事，并且关于这是否是人类中的真实现象的问题仍然存在。在推荐伤口诱导的毛发生长程序作为AGA的疗法之前,需要进一步的临床研究。
