PDF(Pubmed)
Abstract：
Lattice degeneration (LD), routinely diagnosed with indirect ophthalmoscopy, is one of the most common and clinically significant peripheral retinal findings. In this review, we have summarized the data on currently available imaging techniques which help to improve diagnosis and our understanding of LD pathogenesis. Ultra-wide field imaging provides reliable color fundus capturing for the primary diagnosis of LD and may also be used as a screening tool. Wide-field imaging can be used for targeted documentation of LD lesions using true colors and with minimal optical distortions. Information on the status of the vitreoretinal interface, including detection of retinal holes, detachments, and vitreous tractions, can be obtained with peripheral structural optical coherence tomography (OCT) or scanning laser ophthalmoscopy in retro-mode. These techniques clarify the associated risks of rhegmatogenous retinal detachment. Fundus autofluorescence can provide details on atrophic changes. However, the risk of retinal detachment by means of this technique requires further investigation. OCT angiography may be successfully performed for some lesions. Taken together, OCT and OCT angiography demonstrate thinning of the choroid, alteration of local choroidal microcirculation, and, in severe lesions, involvement of the sclera. OCT angiography confirms loss of retinal microcirculation within LD lesion, which was previously shown with fluorescein angiography. In conclusion, despite relatively simple primary diagnosis, imaging of LD lesions remains challenging due to their peripheral localization. However, several new strategies, including ultra-wide field imaging, peripheral OCT, and scanning laser ophthalmoscopy, make LD imaging possible on a routine basis, improving diagnosis and understanding of LD pathogenesis.
摘要：
晶格退化(LD),常规诊断为间接检眼镜，是最常见和临床意义的周边视网膜发现之一。在这次审查中,我们总结了目前可用的影像学技术的数据,这些技术有助于提高诊断水平和我们对LD发病机制的理解.超宽视野成像为LD的初步诊断提供了可靠的彩色眼底捕获，也可以用作筛查工具。宽场成像可用于使用真彩色和最小光学畸变的LD病变的有针对性的文档。玻璃体视网膜界面的状态信息,包括检测视网膜裂孔，分遣队,和玻璃体牵引,可以通过外围结构光学相干断层扫描（OCT）或扫描激光检眼镜在后向模式下获得。这些技术阐明了孔源性视网膜脱离的相关风险。眼底自发荧光可以提供关于萎缩性变化的细节。然而,这种技术导致视网膜脱离的风险需要进一步研究.OCT血管造影可成功用于某些病变。一起来看,OCT和OCT血管造影显示脉络膜变薄，局部脉络膜微循环改变，and,在严重病变中，巩膜的参与。OCT血管造影证实LD病变内视网膜微循环丧失，以前用荧光素血管造影显示。总之,尽管初级诊断相对简单，由于其外周定位,LD病变的成像仍具有挑战性.然而,几个新的战略，包括超宽视场成像，外围OCT,和扫描激光检眼镜，使LD成像成为可能，提高对LD发病机制的诊断和认识。
