Extramedullary hematopoietic pleural effusion in Waldenström's macroglobulinemia.

Waldenstr ö m 巨球蛋白血症的髓外造血胸腔积液。

• 发表时间: 2023 Aug
• 来源期刊: EJHaem
• DOI: 10.1002/jha2.754
• PMID: 37601852
• 文章类型: Case Reports
• 作者列表: Ito K,Harada K,Uchino Y,Hirano K,Sekiguchi N

关键词: 6q deletion; Waldenström's macroglobulinemia; extramedullary hematopoiesis; extramedullary hematopoietic effusion

Abstract

Extramedullary hematopoietic effusion (EHE) is one of the extremely rare phenomena associated with extramedullary hematopoiesis, which is caused by serous effusions, including pleural effusion, and may be related to hematologic disorders and neoplasms. Herein, we present the case of an 81-year-old man with EHE accompanying Waldenström\'s macroglobulinemia (WM). The patient complained of anemia and dyspnea. The chest X-ray and computed tomography showed a massive left pleural effusion, and the aspirates revealed infiltration of the immature myeloid cells and megakaryocytes, in addition to the lymphoma cells. To our knowledge, this is the first report of EHE in WM.

摘要

髓外造血积液（EHE）是与髓外造血有关的极为罕见的现象之一。这是由浆液性积液引起的，包括胸腔积液,可能与血液系统疾病和肿瘤有关。在这里，我们介绍一例81岁男性EHE合并Waldenström巨球蛋白血症(WM)的病例.患者主诉贫血和呼吸困难。胸部X线和计算机断层扫描显示左侧大量胸腔积液，抽吸物显示未成熟的骨髓细胞和巨核细胞浸润，除了淋巴瘤细胞.据我们所知,这是EHE在WM的第一份报告。