PDF(Pubmed)
Abstract：
UNASSIGNED: To evaluate the risk factors and outcomes of central retinal vein occlusion (CRVO) in young patients (< 40 years).
UNASSIGNED: In this retrospective monocentric case series, we included young patients (<40 years) with CRVO. Patients’ medical files were analyzed focusing on demographic characteristics, suspected risk factors, ophthalmic work-up, visual acuity (VA), treatment, and outcomes.
UNASSIGNED: A total of 54 eyes of 52 patients were included. Central retinal vein occlusion was considered idiopathic in 13 patients (25%). The main risk factors identified were ocular hypertension (20.4%), inflammation (20.4%), high blood pressure (14.8%), and coagulation abnormality (11.1%). Final VA was lower in patients with high blood pressure and inflammation when compared to patients with no risk factor (p = 0.03 and 0.04, respectively). Intravitreal injections were needed in 23 eyes (42.6%) and 19 eyes (35.2%) received panretinal photocoagulation treatment.
UNASSIGNED: Central retinal vein occlusion is frequently associated with risk factors in young patients (75% of patients). In addition to the usual factors found in older patients, such as ocular hypertension and high blood pressure, coagulation abnormality and inflammation were also among the risk factors identified. Young patients with CRVO should be evaluated for the presence of risk factors and patients with high blood pressure or inflammatory findings should be followed carefully since they have a worse outcome.
UNASSIGNED: In this retrospective monocentric case series, we included young patients (<40 years) with CRVO. Patients’ medical files were analyzed focusing on demographic characteristics, suspected risk factors, ophthalmic work-up, visual acuity (VA), treatment, and outcomes.
UNASSIGNED: A total of 54 eyes of 52 patients were included. Central retinal vein occlusion was considered idiopathic in 13 patients (25%). The main risk factors identified were ocular hypertension (20.4%), inflammation (20.4%), high blood pressure (14.8%), and coagulation abnormality (11.1%). Final VA was lower in patients with high blood pressure and inflammation when compared to patients with no risk factor (p = 0.03 and 0.04, respectively). Intravitreal injections were needed in 23 eyes (42.6%) and 19 eyes (35.2%) received panretinal photocoagulation treatment.
UNASSIGNED: Central retinal vein occlusion is frequently associated with risk factors in young patients (75% of patients). In addition to the usual factors found in older patients, such as ocular hypertension and high blood pressure, coagulation abnormality and inflammation were also among the risk factors identified. Young patients with CRVO should be evaluated for the presence of risk factors and patients with high blood pressure or inflammatory findings should be followed carefully since they have a worse outcome.
摘要：
■评估年轻患者（<40岁）视网膜中央静脉阻塞（CRVO）的危险因素和预后。
■在这个回顾性的单中心病例系列中，我们纳入了年轻的CRVO患者（<40岁）。患者的医疗档案进行了分析，重点是人口学特征，可疑的危险因素，眼科检查,视敏度（VA），治疗,和结果。
■共纳入52例患者的54只眼。在13例患者（25％）中，视网膜中央静脉阻塞被认为是特发性的。确定的主要危险因素是高眼压（20.4%），炎症（20.4%），高血压(14.8%),和凝血异常(11.1%)。与没有危险因素的患者相比，高血压和炎症患者的最终VA较低（分别为p=0.03和0.04）。23只眼（42.6％）需要玻璃体内注射，19只眼（35.2％）接受了全视网膜光凝治疗。
■视网膜中央静脉阻塞通常与年轻患者（75％的患者）的危险因素有关。除了在老年患者中发现的常见因素外，比如高眼压和高血压，凝血异常和炎症也是确定的危险因素之一.应评估患有CRVO的年轻患者是否存在危险因素，并且应仔细跟踪患有高血压或炎症表现的患者，因为他们的预后较差。
■在这个回顾性的单中心病例系列中，我们纳入了年轻的CRVO患者（<40岁）。患者的医疗档案进行了分析，重点是人口学特征，可疑的危险因素，眼科检查,视敏度（VA），治疗,和结果。
■共纳入52例患者的54只眼。在13例患者（25％）中，视网膜中央静脉阻塞被认为是特发性的。确定的主要危险因素是高眼压（20.4%），炎症（20.4%），高血压(14.8%),和凝血异常(11.1%)。与没有危险因素的患者相比，高血压和炎症患者的最终VA较低（分别为p=0.03和0.04）。23只眼（42.6％）需要玻璃体内注射，19只眼（35.2％）接受了全视网膜光凝治疗。
■视网膜中央静脉阻塞通常与年轻患者（75％的患者）的危险因素有关。除了在老年患者中发现的常见因素外，比如高眼压和高血压，凝血异常和炎症也是确定的危险因素之一.应评估患有CRVO的年轻患者是否存在危险因素，并且应仔细跟踪患有高血压或炎症表现的患者，因为他们的预后较差。
