PDF(Pubmed)
Abstract：
The present report describes a case of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) with pericardial invasion following bone marrow transplantation. The patient exhibited recurrent pericardial effusion accompanied by wheezing symptoms. Despite undergoing multiple pericardial punctures and drainage procedures, pericardial injections, and systemic treatment, the patient continued to experience recurrent pericardial effusion. Ultimately, the patient underwent whole-heart radiotherapy, resulting in complete resolution of the pericardial effusion. After a follow-up period of 10 months, the pericardial effusion remained well-controlled, and there were no significant impairments in cardiac function. In conclusion, radiotherapy may be considered as a viable treatment option for refractory leukemia cases presenting with pericardial effusion.
摘要：
本报告描述了一例费城染色体阳性急性淋巴细胞白血病（PhALL）在骨髓移植后发生心包浸润的病例。患者出现反复的心包积液并伴有喘息症状。尽管接受了多次心包穿刺和引流手术，心包注射,和系统治疗，患者继续出现反复的心包积液。最终,病人接受了全心放疗,导致心包积液完全消退。经过10个月的随访，心包积液控制良好,心功能无明显损伤。总之,对于出现心包积液的难治性白血病患者,放疗可能是一种可行的治疗选择.
