关键词: Acupuncture Anti-inflammatory Mesenchymal stem cell (MSC) Microenvironment Traditional Chinese medicine (TCM)

Mesh : Acupuncture Therapy Medicine, Chinese Traditional Stem Cell Transplantation Cell Differentiation

来  源:   DOI:10.1016/j.lfs.2023.122031

Abstract:
Acupuncture is effective intervention, particularly in nerve, endocrine diseases and immune diseases. The potential mechanisms mediating the effects of acupuncture include anti-inflammatory and oxidative stress, inhibition of cell apoptosis, and stimulation of the proliferation and differentiation of endogenous stem cells. Traditional Chinese medicine combined with stem cell transplantation have a synergistic effect in the treatment of diseases. Increasing studies have found that acupuncture can promote the proliferation, differentiation, homing and survival of exogenous stem cells. This article reviews the mechanism of acupuncture and Chinese herbs on endogenous stem cells and exogenous stem cells in the combined intervention of diverse disorders and the major problems in past 15 years, which will provide a reference for future clinical research.
摘要:
针灸是有效的干预措施,特别是在神经方面,内分泌疾病和免疫性疾病。介导针刺效应的潜在机制包括抗炎和氧化应激,抑制细胞凋亡,和刺激内源性干细胞的增殖和分化。中药联合干细胞移植在疾病医治中具有协同感化。越来越多的研究发现,针灸可以促进增殖,分化,外源性干细胞的归巢和存活。本文综述了近15年来针灸和中药对内源性干细胞和外源性干细胞联合干预多种疾病的作用机制及存在的主要问题。为今后的临床研究提供参考。
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