Abstract：
BACKGROUND: Granulomatous cheilitis is a rare disorder characterized by recurrent, idiopathic, and painless lip swelling. The diagnosis is proven by histopathological examination. The unknown aetiology and poorly understood underlying mechanism contribute to the difficulty in establishing an effective treatment. This case study proposes the effectiveness of radiofrequency therapy in the management of refractory granulomatous cheilitis.
METHODS: A 68-year-old patient presented with hypertrophy and swelling of the lower lip, and a biopsy revealed actinic cheilitis. The patient underwent lip shaving and an advancement mucosal flap, and definitive histologic examination confirmed the diagnosis of granulomatous cheilitis. No other signs of orofacial granulomatosis were observed, and the complementary aetiological study was negative for systemic disease. The lip swelling reappeared and persisted, which interfered with the quality of life. Hence, radiofrequency therapy was performed in the submucosal and subdermal layers of the lip, resulting in significant aesthetic and functional improvement and no further relapses after five years.
CONCLUSIONS: The management of granulomatous cheilitis is challenging. The current mainstay treatment is corticotherapy or reduction cheiloplasty in severe cases. Radiofrequency has potential as a treatment option in debilitating macrocheilia, presenting worthy long-lasting functional and aesthetical results, with minimal morbidity.
METHODS: A 68-year-old patient presented with hypertrophy and swelling of the lower lip, and a biopsy revealed actinic cheilitis. The patient underwent lip shaving and an advancement mucosal flap, and definitive histologic examination confirmed the diagnosis of granulomatous cheilitis. No other signs of orofacial granulomatosis were observed, and the complementary aetiological study was negative for systemic disease. The lip swelling reappeared and persisted, which interfered with the quality of life. Hence, radiofrequency therapy was performed in the submucosal and subdermal layers of the lip, resulting in significant aesthetic and functional improvement and no further relapses after five years.
CONCLUSIONS: The management of granulomatous cheilitis is challenging. The current mainstay treatment is corticotherapy or reduction cheiloplasty in severe cases. Radiofrequency has potential as a treatment option in debilitating macrocheilia, presenting worthy long-lasting functional and aesthetical results, with minimal morbidity.
摘要：
背景：肉芽肿性唇炎是一种罕见的疾病，特发性,和无痛的嘴唇肿胀。诊断通过组织病理学检查证实。病因未知和对潜在机制知之甚少导致难以建立有效的治疗方法。此案例研究提出了射频疗法在难治性肉芽肿性唇炎治疗中的有效性。
方法：一名68岁的患者表现为下唇肥大和肿胀，活检显示光化性唇炎.患者接受了嘴唇剃刮和前移粘膜瓣，明确的组织学检查证实了肉芽肿性唇炎的诊断。没有观察到口面部肉芽肿的其他征象，补充病因研究对全身性疾病阴性。嘴唇肿胀再次出现并持续存在，影响了生活质量.因此，在嘴唇的粘膜下层和真皮下层进行射频治疗，导致显着的美学和功能改善，五年后没有进一步复发。
结论：肉芽肿性唇炎的治疗具有挑战性。在严重病例中，目前的主要治疗方法是皮质治疗或减少唇缘成形术。射频有潜力作为一种治疗方案，呈现值得持久的功能和美学结果，发病率最低。
方法：一名68岁的患者表现为下唇肥大和肿胀，活检显示光化性唇炎.患者接受了嘴唇剃刮和前移粘膜瓣，明确的组织学检查证实了肉芽肿性唇炎的诊断。没有观察到口面部肉芽肿的其他征象，补充病因研究对全身性疾病阴性。嘴唇肿胀再次出现并持续存在，影响了生活质量.因此，在嘴唇的粘膜下层和真皮下层进行射频治疗，导致显着的美学和功能改善，五年后没有进一步复发。
结论：肉芽肿性唇炎的治疗具有挑战性。在严重病例中，目前的主要治疗方法是皮质治疗或减少唇缘成形术。射频有潜力作为一种治疗方案，呈现值得持久的功能和美学结果，发病率最低。
