Abstract:
Brain-related disorders are one of the world\'s most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubarb root that exhibits anti-inflammation, anti-oxidation, anticancer, and neuroprotective properties. A series of preclinical trials have shown EM to have protective benefits against many brain-related diseases. This review has evaluated the potential of EM as a pharmacological agent for the treatment and management of various brain-related disorders based on the findings of multiple pre-clinical studies and taking into account the compound\'s therapeutic properties.
摘要:
脑相关疾病是当今世界上最重要和最复杂的健康问题之一。这些与大脑相关的疾病是造成世界各地大量疾病和死亡的原因。然而,研究人员花了大量的时间来调查这些疾病,并发现了积极的结果;尽管如此,目前有相当多的药物可用于治疗它们。大黄素(EM),多酚化合物,有许多健康益处。它是一种来自大黄根的生物活性单体,具有抗炎作用,抗氧化,抗癌,和神经保护特性。一系列临床前试验表明,EM对许多与大脑相关的疾病具有保护作用。这篇综述基于多项临床前研究的结果并考虑到该化合物的治疗特性,评估了EM作为治疗和管理各种脑相关疾病的药理学药物的潜力。