PDF(Pubmed)
Abstract：
Food safety is a widespread global concern with the emergence of foodborne diseases. Thus, establishing accurate and sensitive detection methods of harmful contaminants in different food matrices is essential to address and prevent the associated health risks. Among various analytical tools, mass spectrometry (MS) can quantify multiple impurities simultaneously due to high resolution and accuracy and can achieve non-target profiling of unknown pollutants in food. Therefore, MS has been widely used for determination of hazardous contaminants [e.g., mycotoxin, pesticide and veterinary drug residues, polychlorinated biphenyls (PCBs), dioxins, acrylamide, perfluorinated compounds (PFCs) and p-Phenylenediamine compounds (PPDs) in food samples]. This work summarizes MS applications in detecting harmful contaminants in food matrices, discusses advantages of MS for food safety study, and provides a perspective on future directions of MS development in food research. With the persistent occurrence of novel contaminants, MS will play a more and more critical role in food analysis.
摘要：
随着食源性疾病的出现,食品安全是全球普遍关注的问题。因此，建立准确，灵敏的检测不同食品基质中有害污染物的方法对于解决和预防相关的健康风险至关重要。在各种分析工具中，质谱（MS）由于高分辨率和准确性，可以同时定量多种杂质，并且可以实现食品中未知污染物的非目标谱分析。因此,MS已广泛用于测定有害污染物[例如，霉菌毒素,农药和兽药残留，多氯联苯（PCBs），二恶英,丙烯酰胺,食品样品中的全氟化合物（PFCs）和对苯二胺化合物（PPD）]。这项工作总结了MS在检测食品基质中有害污染物方面的应用，讨论了MS在食品安全研究中的优势，并对食品研究中MS的未来发展方向提供了展望。随着新型污染物的持续存在，MS将在食品分析中发挥越来越重要的作用。
