Abstract:
Lung cancer is the most diagnosed cancer worldwide. Many non-malignant pulmonary lesions, such as tuberculosis, fungal infection, organizing pneumonia, inflammatory myofibroblastic tumor, and IgG4 disease, can mimic lung cancer due to their overlapping morphological appearance on imaging. These benign entities with minor differentiating imaging clues may go unnoticed in a high-volume cancer institution, leading to over-investigation that may result in repeated biopsies, pointless wedge resections, and related morbidities. However, with a thorough medical history, laboratory diagnostic work-up, and careful analysis of imaging findings, one can occasionally restrict the range of possible diagnoses or arrive at a definitive conclusion. When imaging features overlap, image-guided lung sampling is crucial since histopathological analysis is the gold standard.
摘要:
肺癌是全世界诊断最多的癌症。许多非恶性肺部病变,如肺结核,真菌感染,机化肺炎,炎性肌纤维母细胞瘤,和IgG4病,由于它们在成像上的重叠形态外观,可以模拟肺癌。这些良性实体具有轻微的鉴别成像线索,在高容量的癌症机构中可能不会被注意到,导致过度调查,可能导致重复的活检,无意义的楔形切除,和相关的发病率。然而,有彻底的病史,实验室诊断工作,仔细分析成像结果,人们可以偶尔限制可能的诊断范围或得出明确的结论.当成像特征重叠时,由于组织病理学分析是金标准,因此图像引导的肺取样至关重要.