PDF(Pubmed)
Abstract：
Bacterial vaginosis (BV) is the most common vaginal infection worldwide. It is associated with an increased risk of acquisition of HIV and other sexually transmitted infections (STIs) as well as pelvic inflammatory disease and adverse birth outcomes. During BV, a polymicrobial biofilm forms on the surface of the vaginal mucosa. However, the exact etiology of BV remains controversial which has impeded significant advances in diagnosis, treatment, and prevention. Despite 30-day cure rates approaching 80% in BV-infected women treated with 7 days of oral metronidazole, recurrence within 12 months is common. This article provides a current review of the epidemiology, pathogenesis, diagnosis, and treatment of recurrent BV for practicing clinicians who commonly see women with this recurrent vaginal infection. Regarding management, we focus primarily on antimicrobial measures that may be effective. Future areas of research in this field are also discussed.
摘要：
细菌性阴道病（BV）是全球最常见的阴道感染。它与HIV和其他性传播感染（STIs）以及盆腔炎和不良出生结局的风险增加有关。在BV期间,在阴道粘膜的表面上形成多微生物生物膜。然而,BV的确切病因仍然存在争议，这阻碍了诊断的重大进展，治疗,和预防。尽管口服甲硝唑治疗7天的BV感染妇女的30天治愈率接近80％，12个月内复发是常见的。本文提供了当前的流行病学综述，发病机制，诊断,和复发性BV的治疗，这些临床医生通常看到患有这种复发性阴道感染的女性。关于管理，我们主要关注可能有效的抗菌措施。还讨论了该领域的未来研究领域。
