PDF(Pubmed)
Abstract：
UNASSIGNED: Antibiotic resistance has become an issue of global importance due to increasing levels of bacterial infections worldwide. Farm management and usage of antibiotics in livestock are known risk factors associated with the increase in global levels of antibiotic resistance. Goats and sheep are examples of livestock with large populations. Although antibiotic resistance in bacteria from livestock negatively affects both human health and the economy, the global data regarding this issue in goats and sheep are limited. Therefore, this study aimed to provide information on the antibiotic-resistance profile of bacteria isolated from goats and sheep worldwide (Asia, Europe, and Africa).
UNASSIGNED: We performed a systematic review of articles published on this topic without any restriction on the year of publication. We searched the Directory of Open Access Journals, PubMed, Google Scholar, and Scopus using Boolean logic through various keywords. The search generated a total of 1325 articles, and after screening for duplicates and implementing inclusion and exclusion criteria, qualitative synthesis (i.e., qualitative systematic review) was performed on 37 articles.
UNASSIGNED: The synthesized information indicated that 18 Gram-positive and 13 Gram-negative bacterial species from goats and sheep were resistant to ten antibiotics, namely penicillin, ampicillin, amoxicillin, chloramphenicol, streptomycin, tetracycline, cephalothin, gentamicin, ciprofloxacin (CIP), and sulfamethoxazole. The prevalence of antibiotic resistance ranged from 0.4% to 100%. However, up to 100% of some bacteria, namely, Salmonella Dublin, Aeromonas caviae, and Aeromonas sobria, were susceptible to CIP. Staphylococcus aureus and Escherichia coli were highly resistant to all antibiotics tested. Moreover, eight of the ten antibiotics tested were critically important antibiotics for humans.
UNASSIGNED: Antibiotic-resistant bacteria in goats and sheep are a potential risk to animal and human health. Collaboration between all stakeholders and further research is needed to prevent the negative impacts of antibiotic resistance.
UNASSIGNED: We performed a systematic review of articles published on this topic without any restriction on the year of publication. We searched the Directory of Open Access Journals, PubMed, Google Scholar, and Scopus using Boolean logic through various keywords. The search generated a total of 1325 articles, and after screening for duplicates and implementing inclusion and exclusion criteria, qualitative synthesis (i.e., qualitative systematic review) was performed on 37 articles.
UNASSIGNED: The synthesized information indicated that 18 Gram-positive and 13 Gram-negative bacterial species from goats and sheep were resistant to ten antibiotics, namely penicillin, ampicillin, amoxicillin, chloramphenicol, streptomycin, tetracycline, cephalothin, gentamicin, ciprofloxacin (CIP), and sulfamethoxazole. The prevalence of antibiotic resistance ranged from 0.4% to 100%. However, up to 100% of some bacteria, namely, Salmonella Dublin, Aeromonas caviae, and Aeromonas sobria, were susceptible to CIP. Staphylococcus aureus and Escherichia coli were highly resistant to all antibiotics tested. Moreover, eight of the ten antibiotics tested were critically important antibiotics for humans.
UNASSIGNED: Antibiotic-resistant bacteria in goats and sheep are a potential risk to animal and human health. Collaboration between all stakeholders and further research is needed to prevent the negative impacts of antibiotic resistance.
摘要：
■由于全球范围内细菌感染水平的增加，抗生素耐药性已成为全球重要的问题。农场管理和牲畜抗生素的使用是已知的与全球抗生素耐药性水平增加相关的风险因素。山羊和绵羊是人口众多的牲畜的例子。尽管家畜细菌的抗生素耐药性对人类健康和经济都有负面影响，关于山羊和绵羊这一问题的全球数据是有限的。因此,这项研究旨在提供全球从山羊和绵羊中分离出的细菌的抗生素抗性概况的信息(亚洲，欧洲,和非洲）。
■我们对有关该主题的文章进行了系统的审查，对发表年份没有任何限制。我们搜索了开放获取期刊目录，PubMed,谷歌学者，和Scopus通过各种关键字使用布尔逻辑。搜索共产生1325篇文章，在筛选重复项并执行纳入和排除标准后，定性合成(即，定性系统评价)对37篇文章进行。
■合成的信息表明，来自山羊和绵羊的18种革兰氏阳性细菌和13种革兰氏阴性细菌对十种抗生素具有抗性，即青霉素,氨苄青霉素,阿莫西林,氯霉素,链霉素,四环素,头孢菌素,庆大霉素,环丙沙星(CIP),和磺胺甲恶唑.抗生素耐药性的患病率为0.4％至100％。然而,高达100%的细菌，即,都柏林沙门氏菌,鱼气单胞菌,和嗜水气单胞菌,易感CIP.金黄色葡萄球菌和大肠杆菌对所有测试的抗生素均具有高度耐药性。此外，测试的十种抗生素中有八种是对人类至关重要的抗生素。
■山羊和绵羊体内的抗生素抗性细菌对动物和人类健康具有潜在的风险。所有利益相关者之间的合作和进一步的研究是必要的，以防止抗生素耐药性的负面影响。
■我们对有关该主题的文章进行了系统的审查，对发表年份没有任何限制。我们搜索了开放获取期刊目录，PubMed,谷歌学者，和Scopus通过各种关键字使用布尔逻辑。搜索共产生1325篇文章，在筛选重复项并执行纳入和排除标准后，定性合成(即，定性系统评价)对37篇文章进行。
■合成的信息表明，来自山羊和绵羊的18种革兰氏阳性细菌和13种革兰氏阴性细菌对十种抗生素具有抗性，即青霉素,氨苄青霉素,阿莫西林,氯霉素,链霉素,四环素,头孢菌素,庆大霉素,环丙沙星(CIP),和磺胺甲恶唑.抗生素耐药性的患病率为0.4％至100％。然而,高达100%的细菌，即,都柏林沙门氏菌,鱼气单胞菌,和嗜水气单胞菌,易感CIP.金黄色葡萄球菌和大肠杆菌对所有测试的抗生素均具有高度耐药性。此外，测试的十种抗生素中有八种是对人类至关重要的抗生素。
■山羊和绵羊体内的抗生素抗性细菌对动物和人类健康具有潜在的风险。所有利益相关者之间的合作和进一步的研究是必要的，以防止抗生素耐药性的负面影响。
