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Abstract：
Introduction Endometrial aspiration cytology (EAC) is a noninvasive, rapid, and cost-effective procedure for diagnosing gynecological disorders. This study aimed to validate endometrial aspiration as a routine, safe, and efficient outpatient diagnostic procedure, correlating its findings with histopathology evaluations to facilitate early surgical planning for patients with abnormal uterine bleeding. Materials and methods This cross-sectional study involved patients of reproductive, menopausal, and postmenopausal age groups who presented with diverse gynecological concerns that required dilatation and curettage. Endometrial aspiration was performed using a Karman cannula (Angiplast Pvt. Ltd., Vatva, India), and the obtained material was prepared into smears and stained for evaluation. Sampling adequacy, the nature of glandular and stromal cells, phasing of the endometrium, and other abnormalities were assessed and correlated with histology to examine the diagnostic utility of endometrial cytology. Results EAC showed 90.66% sampling adequacy with the Karman cannula. The sensitivity of EAC for diagnosing benign and malignant conditions was 88.7% and 100%, respectively. Conditions including secretory endometrium, proliferative phase, tuberculous endometritis, and glandular hyperplasia were diagnosed using EAC and confirmed by histopathology. Six malignancies were successfully diagnosed on cytology smears, while challenges in differentiation and sampling errors were recognized as limitations of the technique. Conclusions This study established EAC as a highly sensitive, minimally invasive preliminary diagnostic tool for gynecological disorders, particularly effective in diagnosing malignancy. Despite certain limitations, the procedure\'s ease, cost-effectiveness, and safety underscore its potential for routine use by surgeons.
摘要：
简介子宫内膜抽吸细胞学（EAC）是一种非侵入性，快速,和具有成本效益的诊断妇科疾病的程序。这项研究旨在验证子宫内膜抽吸作为常规，安全,和有效的门诊诊断程序，将其发现与组织病理学评估相关联，以促进异常子宫出血患者的早期手术计划。材料和方法这项横断面研究涉及生殖，更年期,以及绝经后年龄组，他们有不同的妇科问题，需要扩张和刮宫。使用Karman套管进行子宫内膜抽吸（血管成形术。Ltd.,Vatva,印度),并将获得的材料制成涂片并染色用于评估。采样充分性，腺细胞和基质细胞的性质，子宫内膜的分期，和其他异常进行了评估，并与组织学相关联，以检查子宫内膜细胞学的诊断效用。结果EAC显示使用Karman套管的采样充分性为90.66％。EAC诊断良恶性的敏感性分别为88.7%和100%,分别。条件包括分泌性子宫内膜，增殖期，结核性子宫内膜炎,使用EAC诊断腺体增生，并通过组织病理学证实。在细胞学涂片上成功诊断出六例恶性肿瘤,而区分和抽样误差方面的挑战被认为是该技术的局限性。结论本研究确立了EAC作为一种高度敏感的,妇科疾病的微创初步诊断工具，对诊断恶性肿瘤特别有效。尽管有一定的局限性,程序的简化，成本效益，和安全性强调了外科医生常规使用它的潜力。
