关键词: avascular necrosis dermal hypersensitivity fibrinoid iga-mediated immune complex leukocytocsis vasculitis neutrophils raynaud's phenomenon skin necrosis systemic

来  源:   DOI:10.7759/cureus.41736   PDF(Pubmed)

Abstract:
Leukocytoclastic vasculitis, also known as hypersensitivity angiitis, is a cutaneous, small vessel vasculitis of the dermal capillaries and venules. The predominant clinical presentation is palpable purpura. Multiple medications can cause leukocytoclastic vasculitis, as well as autoimmune diseases, infections, and malignancy. The disease process may be limited to only the skin or a manifestation of a systemic vasculitis or process. Treatment is centered on symptom management. Our patient is a 60-year-old female who presented with bilateral dry and wet tender ulcerations. She was previously treated with paclizumab.
摘要:
白细胞碎裂性血管炎,也被称为过敏性血管炎,是皮肤,真皮毛细血管和小静脉的小血管炎。主要的临床表现是明显的紫癜。多种药物可引起白细胞碎裂性血管炎,以及自身免疫性疾病,感染,和恶性肿瘤。疾病过程可能仅限于皮肤或全身性血管炎或过程的表现。治疗以症状管理为中心。我们的患者是一名60岁的女性,患有双侧干性和湿性溃疡。她以前接受过帕利珠单抗治疗。
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