PDF(Pubmed)
Abstract：
Herein, we describe the management of nasopharyngitis caused by Schizophyllum commune infection in a captive cheetah. Computed tomography revealed a nodule in the nasal cavity and pharynx, and an endoscopic biopsy was performed. As a result, the nodule was surgically resected because of a suspected carcinoma. However, the surgical specimen was histologically re-evaluated and a fungal granuloma was diagnosed. Sequence analysis of DNA from formalin-fixed, paraffin-embedded samples revealed S. commune infection. The cheetah was administered fluconazole orally for 73 days. However, the drug was ineffective and itraconazole was administered for 14 days. Symptoms such as nasal discharge and sneezing have completely resolved for 4 years.
摘要：
在这里，我们描述了在圈养的猎豹中由裂殖菌社区感染引起的鼻咽炎的管理。计算机断层扫描显示鼻腔和咽部有结节，并进行了内窥镜活检。因此,由于怀疑有癌症，结节被手术切除。然而,对手术标本进行组织学重新评估，并诊断为真菌性肉芽肿。福尔马林固定的DNA序列分析，石蜡包埋的样本显示S.commune感染。猎豹口服氟康唑73天。然而,药物无效，伊曲康唑给药14天。流鼻涕和打喷嚏等症状已经完全解决了4年。
