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Abstract：
BACKGROUND: Few studies have identified the links between physical activity (PA), clinical symptoms, and the quality of life (QoL) among mildly infected individuals with COVID-19. This cross-sectional study aims to evaluate how PA levels before infections affect the infectious symptoms and the QoL in mildly infected patients with COVID-19.
METHODS: An online questionnaire link including participants\' sociodemographic and anthropometric characteristics, clinical symptoms during the COVID-19 infectious period, the QoL of the worst symptomatic day, and PA in the last seven days before COVID-19 infections was disclosed. Logistic regression and multiple linear regression analyses were applied to assess the relationships between PA levels in the last seven days before infections and COVID-19-related outcomes. The level of statistical significance was set at p < 0.05.
RESULTS: Compared to the low-PA-level group, the moderate-PA-level group presented a higher risk of headaches (OR = 1.34, 95% CI = 1.03 to 1.75, and p = 0.03) and the high-PA-level group presented a higher risk of muscle/body aches (OR = 1.42, 95% CI = 1.04 to 1.93, and p = 0.03). The adjusted linear regression analysis showed that no associations were found between PA levels in the last seven days before infections and the QoL index value on the worst symptomatic day (moderate-PA-level group: β = -0.04, and p = 0.08; high-PA-level group: β = -0.04, and p = 0.17). However, for the mobility and usual activities dimensions of EQ-5D-5L, the lower-PA-level group had a lower burden of QoL than the higher-PA-level group did on the worst-symptomatic day.
CONCLUSIONS: Among mildly infected patients with COVID-19, a higher PA level is associated with a higher risk of experiencing clinical symptoms and a lower QoL.
METHODS: An online questionnaire link including participants\' sociodemographic and anthropometric characteristics, clinical symptoms during the COVID-19 infectious period, the QoL of the worst symptomatic day, and PA in the last seven days before COVID-19 infections was disclosed. Logistic regression and multiple linear regression analyses were applied to assess the relationships between PA levels in the last seven days before infections and COVID-19-related outcomes. The level of statistical significance was set at p < 0.05.
RESULTS: Compared to the low-PA-level group, the moderate-PA-level group presented a higher risk of headaches (OR = 1.34, 95% CI = 1.03 to 1.75, and p = 0.03) and the high-PA-level group presented a higher risk of muscle/body aches (OR = 1.42, 95% CI = 1.04 to 1.93, and p = 0.03). The adjusted linear regression analysis showed that no associations were found between PA levels in the last seven days before infections and the QoL index value on the worst symptomatic day (moderate-PA-level group: β = -0.04, and p = 0.08; high-PA-level group: β = -0.04, and p = 0.17). However, for the mobility and usual activities dimensions of EQ-5D-5L, the lower-PA-level group had a lower burden of QoL than the higher-PA-level group did on the worst-symptomatic day.
CONCLUSIONS: Among mildly infected patients with COVID-19, a higher PA level is associated with a higher risk of experiencing clinical symptoms and a lower QoL.
摘要：
背景：很少有研究确定身体活动（PA）之间的联系，临床症状,和COVID-19轻度感染个体的生活质量（QoL）。这项横断面研究旨在评估感染前PA水平如何影响轻度感染COVID-19患者的感染症状和QoL。
方法：在线问卷链接，包括参与者的社会人口统计学和人体测量特征，COVID-19感染期间的临床症状，症状最严重的一天的QoL，和PA在COVID-19感染被披露前的最后七天。采用Logistic回归和多元线性回归分析评估感染前7天PA水平与COVID-19相关结局之间的关系。统计显著性水平设定为p<0.05。
结果：与低PA水平组相比，中等PA水平组出现头痛的风险较高(OR=1.34,95%CI=1.03~1.75,p=0.03),高PA水平组出现肌肉/身体疼痛的风险较高(OR=1.42,95%CI=1.04~1.93,p=0.03).调整后的线性回归分析显示，感染前最后7天的PA水平与症状最严重日的QoL指数值之间未发现关联（中度PA水平组：β=-0.04，p=0.08；高PA水平组：β=-0.04，p=0.17）。然而,对于EQ-5D-5L的机动性和通常的活动尺寸，在症状最严重的当天,PA水平较低的组的QoL负担低于PA水平较高的组.
结论：在轻度感染COVID-19的患者中，较高的PA水平与出现临床症状的风险较高和较低的QoL相关。
方法：在线问卷链接，包括参与者的社会人口统计学和人体测量特征，COVID-19感染期间的临床症状，症状最严重的一天的QoL，和PA在COVID-19感染被披露前的最后七天。采用Logistic回归和多元线性回归分析评估感染前7天PA水平与COVID-19相关结局之间的关系。统计显著性水平设定为p<0.05。
结果：与低PA水平组相比，中等PA水平组出现头痛的风险较高(OR=1.34,95%CI=1.03~1.75,p=0.03),高PA水平组出现肌肉/身体疼痛的风险较高(OR=1.42,95%CI=1.04~1.93,p=0.03).调整后的线性回归分析显示，感染前最后7天的PA水平与症状最严重日的QoL指数值之间未发现关联（中度PA水平组：β=-0.04，p=0.08；高PA水平组：β=-0.04，p=0.17）。然而,对于EQ-5D-5L的机动性和通常的活动尺寸，在症状最严重的当天,PA水平较低的组的QoL负担低于PA水平较高的组.
结论：在轻度感染COVID-19的患者中，较高的PA水平与出现临床症状的风险较高和较低的QoL相关。
