PDF(Pubmed)
Abstract：
Breast cancer was identified as the cancer with the highest mortality rate among women in Brazil. This study analyzed the effects of age, period and birth cohort on the breast cancer mortality rate for Brazilian women, comparing state capitals and non-capital municipalities. Population and deaths data were extracted from the Brazilian Unified Health System database for women aged 30 years or older, for the years between 1980 and 2019. The effects were analyzed using the age-period-cohort model. Age effect on breast cancer mortality is observed in the model through higher mortality rates at older ages. Period effect is similar in all regions in the form of a marked increase in the rate ratio (RR) in non-capital municipalities by period than in state capitals. The RR of birth cohorts in the state capitals remained stable (north, northeast and central-west regions) or decreased followed by an increase in the most recent cohorts (Brazil as a whole and the southeast and south regions). The RR for the other municipalities, however, showed a progressive increase in the cohorts for all regions. Policies and actions focused on breast cancer in women should consider these differences among Brazilian regions, state capitals and other municipalities.
摘要：
乳腺癌被确定为巴西女性死亡率最高的癌症。这项研究分析了年龄的影响，关于巴西女性乳腺癌死亡率的时期和出生队列，比较州府和非首都城市。从巴西统一卫生系统数据库中提取了30岁或以上女性的人口和死亡数据，从1980年到2019年。使用年龄-时期-队列模型分析效果。在该模型中,通过年龄较大时的较高死亡率观察到年龄对乳腺癌死亡率的影响。在所有地区，期间效应都相似，非首都城市的比率（RR）比州首府显着增加。州首府出生队列的RR保持稳定(北部，东北和中西部地区）或减少，然后在最近的队列中（整个巴西以及东南和南部地区）增加。其他城市的RR，然而,显示所有地区的队列都有逐步增加。针对女性乳腺癌的政策和行动应考虑巴西各地区之间的这些差异，州首府和其他城市。
