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Abstract：
The aim of this retrospective cross-sectional study was to comprehensively assess masticatory function in maxillectomy patients with functioning removable prostheses. Their general and oral profiles, the measurement values of their oral functions, including masticatory function, and the history of tumor therapy were extracted from medical charts. The correlations of masticatory function with numerical data and the effects of tumor therapy-related factors on masticatory function were evaluated. In addition, a stepwise conditional logistic regression analysis was performed to identify the potential predictive factors comprehensively. The data from 55 maxillectomy patients revealed that the median value of masticatory function (138.0 mg/dL) was higher than the threshold (100.0 mg/dL) based on the concept of oral hypofunction. Moderate correlations of masticatory function with the number of remaining teeth, the number of functioning occlusal supports, and maximum occlusal force were found, as well as a weak correlation with maximum tongue pressure. These variables also showed statistically significant coefficients (p < 0.01). No significant effect of each tumor therapy-related factor on masticatory function was detected. A logistic regression analysis identified the number of functioning occlusal supports as a significant predictive factor. These results implied the crucial interactions of masticatory function with various factors and the specificities of maxillectomy patients.
摘要：
这项回顾性横断面研究的目的是全面评估具有功能性可移动假体的上颌切除术患者的咀嚼功能。他们的一般和口腔概况，他们口腔功能的测量值，包括咀嚼功能，并从病历中提取肿瘤治疗史。评估咀嚼功能与数值数据的相关性以及肿瘤治疗相关因素对咀嚼功能的影响。此外,我们进行了逐步条件logistic回归分析,以全面识别潜在的预测因素.来自55例上颌骨切除术患者的数据显示，基于口腔功能减退的概念，咀嚼功能的中位值（138.0mg/dL）高于阈值（100.0mg/dL）。咀嚼功能与剩余牙齿数量的中等相关性，功能咬合支撑的数量，发现了最大的咬合力，以及与最大舌头压力的弱相关性。这些变量也显示出统计学上显著的系数(p<0.01)。未检测到每种肿瘤治疗相关因子对咀嚼功能的显着影响。逻辑回归分析确定了功能性咬合支持的数量是一个重要的预测因素。这些结果暗示了咀嚼功能与各种因素以及上颌骨切除术患者的特异性之间的关键相互作用。
