Abstract：
OBJECTIVE: Hemicrania Continua (HC) is a rare and disabling primary headache disorder that is characterized by persistent, unilateral headache with ipsilateral, cranial autonomic symptoms and restlessness or agitation. The diagnosis requires patients to experience an absolute response to therapeutic doses of indomethacin.
RESULTS: HC is diagnosed in in about 1.8% of adult patients who were evaluated for headache in tertiary care services, albeit this estimate should be interpreted with caution. The most prevalent accompanying symptoms appear to be lacrimation, conjunctival injection and restlessness or agitation. However, the available literature is limited by methodologic issues, and the current diagnostic criteria lack clarity on what defines absolute response to indomethacin. More rigorous studies are thus needed to improve our understanding of HC which, in turn, will facilitate better disease management in clinical practice. Here, we provide a comprehensive overview of HC, including its epidemiology, clinical presentation, diagnostic evaluation, and management.
RESULTS: HC is diagnosed in in about 1.8% of adult patients who were evaluated for headache in tertiary care services, albeit this estimate should be interpreted with caution. The most prevalent accompanying symptoms appear to be lacrimation, conjunctival injection and restlessness or agitation. However, the available literature is limited by methodologic issues, and the current diagnostic criteria lack clarity on what defines absolute response to indomethacin. More rigorous studies are thus needed to improve our understanding of HC which, in turn, will facilitate better disease management in clinical practice. Here, we provide a comprehensive overview of HC, including its epidemiology, clinical presentation, diagnostic evaluation, and management.
摘要：
目的：连续性偏头痛（HC）是一种罕见且致残的原发性头痛，同侧单侧头痛，头颅自主神经症状和躁动或躁动。诊断要求患者对消炎痛的治疗剂量有绝对反应。
结果：在三级护理服务中接受过头痛评估的成年患者中约有1.8％被诊断为HC，尽管这一估计应该谨慎解释。最普遍的伴随症状似乎是流泪，结膜注射和躁动或激动。然而,现有文献受到方法学问题的限制，而目前的诊断标准对吲哚美辛的绝对反应定义缺乏明确性.因此，需要更严格的研究来提高我们对HC的理解，反过来,将促进临床实践中更好的疾病管理。这里,我们提供了HC的全面概述，包括它的流行病学,临床表现,诊断评估,和管理。
结果：在三级护理服务中接受过头痛评估的成年患者中约有1.8％被诊断为HC，尽管这一估计应该谨慎解释。最普遍的伴随症状似乎是流泪，结膜注射和躁动或激动。然而,现有文献受到方法学问题的限制，而目前的诊断标准对吲哚美辛的绝对反应定义缺乏明确性.因此，需要更严格的研究来提高我们对HC的理解，反过来,将促进临床实践中更好的疾病管理。这里,我们提供了HC的全面概述，包括它的流行病学,临床表现,诊断评估,和管理。
