PDF(Pubmed)
Abstract：
Disease severity assessment tools play a large part in evaluating skin conditions in dermatology. Currently, there is no existing validated assessment tool for keratosis pilaris (KP), a benign yet highly prevalent follicular disorder. A range of proposed scoring tools have been used in different clinical trials for the assessment of potential treatments for KP. A literature review of the current scoring systems used for KP shows that there is a lack of consistency with most studies using varying versions of unvalidated investigator global assessment (IGA) scores and quartile grading systems. A review of these studies shows that current methods of evaluating KP in clinical trials are subjective, unreliable, and inconsistent. A standardised and validated scoring system would be significant as it could be used in clinical trials to advance the current knowledge of KP.
摘要：
疾病严重程度评估工具在评估皮肤病学的皮肤状况中起着很大的作用。目前,目前尚无经过验证的毛发角化病（KP）评估工具，良性但高度流行的卵泡疾病。一系列提出的评分工具已在不同的临床试验中用于评估KP的潜在治疗。对用于KP的当前评分系统的文献综述表明，与使用不同版本的未经验证的研究者全球评估（IGA）评分和四分位数评分系统的大多数研究缺乏一致性。对这些研究的回顾表明，目前在临床试验中评估KP的方法是主观的，不可靠,和不一致。标准化和验证的评分系统将是重要的，因为它可以用于临床试验以提高KP的当前知识。
