PDF(Pubmed)
Abstract：
UNASSIGNED: The management of anticoagulation for mechanical heart valves (MHVs) during pregnancy posed a special challenge. Mechanical thrombectomy (MT) was the standard treatment for acute ischemic stroke (AIS) in anterior circulation with large vessel occlusion. However, the efficacy and safety of MT in the treatment of acute ischemic stroke in pregnancy were unknown.
UNASSIGNED: A 29-year-old woman with MHVs in her first pregnancy at 7 weeks\' gestation underwent MT because of a large occlusive thrombus in the end of the internal carotid artery despite therapeutic anticoagulation with low-molecular-weight heparin. This pregnant woman recovered well after MT with a modified rank score (mRS) of 0 at 90 days.
UNASSIGNED: At present, there was no standard protocol of anticoagulation therapy for pregnant women with MHVs. Acute ischemic stroke with large vessel occlusion in pregnancy was rare, but could bring devastating consequences for both mother and infant. Our case report demonstrated that MT could be safe and effective in pregnancy.
UNASSIGNED: A 29-year-old woman with MHVs in her first pregnancy at 7 weeks\' gestation underwent MT because of a large occlusive thrombus in the end of the internal carotid artery despite therapeutic anticoagulation with low-molecular-weight heparin. This pregnant woman recovered well after MT with a modified rank score (mRS) of 0 at 90 days.
UNASSIGNED: At present, there was no standard protocol of anticoagulation therapy for pregnant women with MHVs. Acute ischemic stroke with large vessel occlusion in pregnancy was rare, but could bring devastating consequences for both mother and infant. Our case report demonstrated that MT could be safe and effective in pregnancy.
摘要：
■妊娠期间机械心脏瓣膜（MHV）的抗凝管理提出了特殊的挑战。机械血栓切除术（MT）是前循环大血管闭塞的急性缺血性卒中（AIS）的标准治疗方法。然而,MT治疗妊娠期急性缺血性卒中的有效性和安全性未知.
■一名29岁女性在妊娠7周时首次怀孕时，由于颈内动脉末端有大量闭塞性血栓，尽管使用了低分子量肝素进行了抗凝治疗，但仍接受了MT。该孕妇在MT后恢复良好，90天时的等级评分（mRS）为0。
■目前，对于患有MHV的孕妇,没有标准的抗凝治疗方案.妊娠合并大血管闭塞的急性缺血性卒中罕见，但可能给母亲和婴儿带来毁灭性的后果。我们的病例报告表明，MT在怀孕期间可能是安全有效的。
■一名29岁女性在妊娠7周时首次怀孕时，由于颈内动脉末端有大量闭塞性血栓，尽管使用了低分子量肝素进行了抗凝治疗，但仍接受了MT。该孕妇在MT后恢复良好，90天时的等级评分（mRS）为0。
■目前，对于患有MHV的孕妇,没有标准的抗凝治疗方案.妊娠合并大血管闭塞的急性缺血性卒中罕见，但可能给母亲和婴儿带来毁灭性的后果。我们的病例报告表明，MT在怀孕期间可能是安全有效的。
