PDF(Pubmed)
Abstract：
Non-ossifying fibromas usually occur in the metaphysis of the long bones in children, and are extremely rare in the mandible. Here, we present a case of non-ossifying fibromas which occurred in the mandible of a 4-year-old boy. The patient had no complaint of ache. Laboratory blood examination of serum calcium, phosphorus, and parathormone levels was normal. Computed tomography of the maxillofacial region showed a well-defined osteolytic lesion affecting the right mandible. Microscopically, the lesion showed whorled bundles of spindle-shaped fibroblasts, as well as foam cells, mingled with scant multinucleated giant cells, without any bone formation. It is necessary to distinguish non-ossifying fibromas from other giant cell-containing lesions because of the extremely infrequent occurrence of this lesion in the mandible. We reviewed the histologic features of 14 cases of non-ossifying fibromas involved in the jaw.
摘要：
非骨化性纤维瘤通常发生在儿童长骨干，在下颌骨中极为罕见。这里,我们介绍了一例发生在4岁男孩下颌骨中的非骨化纤维瘤。病人没有疼痛的主诉。血清钙的实验室血液检查，磷，副激素水平正常.颌面部区域的计算机断层扫描显示出明确的溶骨性病变，影响了右下颌骨。微观上,病变显示梭形成纤维细胞的轮生束，以及泡沫细胞，混合了很少的多核巨细胞，没有任何骨骼形成。由于下颌骨中很少发生这种病变，因此有必要将非骨化性纤维瘤与其他含巨细胞的病变区分开。我们回顾了14例非骨化性颌骨纤维瘤的组织学特征。
