关键词: Infectious diseases coronavirus disease 2019 (COVID-19) multi-source dynamic ensemble prediction (MDEP) multiwave

来  源:   DOI:10.21037/jtd-23-234   PDF(Pubmed)

Abstract:
UNASSIGNED: The development of an epidemic always exhibits multiwave oscillation owing to various anthropogenic sources of transmission. Particularly in populated areas, the large-scaled human mobility led to the transmission of the virus faster and more complex. The accurate prediction of the spread of infectious diseases remains a problem. To solve this problem, we propose a new method called the multi-source dynamic ensemble prediction (MDEP) method that incorporates a modified susceptible-exposed-infected-removed (SEIR) model to improve the accuracy of the prediction result.
UNASSIGNED: The modified SEIR model is based on the compartment model, which is suitable for local-scale and confined spaces, where human mobility on a large scale is not considered. Moreover, compartmental models cannot be used to predict multiwave epidemics. The proposed MDEP method can remedy defects in the compartment model. In this study, multi-source prediction was made on the development of coronavirus disease 2019 (COVID-19) and dynamically assembled to obtain the final integrated result. We used the real epidemic data of COVID-19 in three cities in China: Beijing, Lanzhou, and Beihai. Epidemiological data were collected from 17 April, 2022 to 12 August, 2022.
UNASSIGNED: Compared to the one-wave modified SEIR model, the MDEP method can depict the multiwave development of COVID-19. The MDEP method was applied to predict the number of cumulative cases of recent COVID-19 outbreaks in the aforementioned cities in China. The average accuracy rates in Beijing, Lanzhou, and Beihai were 89.15%, 91.74%, and 94.97%, respectively.
UNASSIGNED: The MDEP method improved the prediction accuracy of COVID-19. With further application to other infectious diseases, the MDEP method will provide accurate predictions of infectious diseases and aid governments make appropriate directives.
摘要:
由于各种人为传播源,流行病的发展总是表现出多波振荡。特别是在人口稠密的地区,人类的大规模流动导致病毒的传播更快、更复杂。准确预测传染病的传播仍然是一个问题。为了解决这个问题,我们提出了一种称为多源动态集成预测(MDEP)方法的新方法,该方法结合了改进的易感暴露感染去除(SEIR)模型,以提高预测结果的准确性。
修改后的SEIR模型基于隔室模型,适用于局部尺度和密闭空间,没有考虑大规模的人类流动性。此外,隔室模型不能用于预测多波流行病。提出的MDEP方法可以弥补隔室模型中的缺陷。在这项研究中,对2019年冠状病毒病(COVID-19)的发展进行多源预测,并动态组装以获得最终的综合结果。我们使用了中国三个城市的COVID-19的真实疫情数据:北京,兰州和北海。从4月17日开始收集流行病学数据,2022年8月12日,2022年。
与单波修改的SEIR模型相比,MDEP方法可以描述COVID-19的多波发展。MDEP方法用于预测中国上述城市近期COVID-19暴发的累积病例数。北京的平均准确率,兰州北海占89.15%,91.74%,94.97%,分别。
MDEP方法提高了COVID-19的预测精度。随着对其他传染病的进一步应用,MDEP方法将提供对传染病的准确预测,并帮助政府制定适当的指令。
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