关键词: collagen crosslinking corneal ectasia intracorneal ring keratoconus refractive surgery

来  源:   DOI:10.1515/abm-2022-0035   PDF(Pubmed)

Abstract:
UNASSIGNED: Studies in the epidemiology of keratoconus are limited in Southeast Asia. A study on the prevalence and characteristics of keratoconus in the Thai population could give a general idea of its impact.
UNASSIGNED: To study keratoconus prevalence in patients seeking refractive surgery and analyze the characteristics of keratoconus.
UNASSIGNED: Medical records from April 2015 to August 2018 were retrospectively reviewed. Keratoconus and keratoconus suspect prevalence in patients seeking laser vision correction were calculated. The characteristics of keratoconus patients were reviewed. The Amsler-Krumeich classification was used to determine the stages. Topographically, the types of cones were categorized into oval, nipple, pellucid marginal degeneration (PMD)-like, and astigmatic types.
UNASSIGNED: Keratoconus and keratoconus suspect prevalence were 1.66% and 0.68%, respectively. Out of the affected patients, 73.8% were male. The mean age at diagnosis was 25.25 ± 8.35 years. The presenting symptoms were blurred vision (87%) and itching (47%). Stage 1 was predominant, found in 39% of patients (followed by stages 2, 4, and 3, respectively). Ocular findings comprised the Munson sign (14.63%), the Rizutti sign (6.94%), Fleischer ring (28.14%), Vogt striae (24.95%), corneal scar (8.63%), prominent corneal nerve (2.81%), and corneal staining (7.69%). Mean uncorrected visual acuity (logarithm of the minimum angle of resolution [logMAR]) was 0.88 ± 0.64. Mean corrected visual acuity (logMAR) was 0.40 ± 0.49. Mean Q-value was -0.92 ± 0.63. The thinnest pachymetry was 459.39 ± 56.96 microns. The mean keratometry was 49.7 ± 6.64 diopters. Topographically, the types of cones were oval (57%), astigmatic (33%), PMD-like (5%), and nipple type (4%).
UNASSIGNED: Keratoconus prevalence among Thai patients seeking refractive surgery was 1.66%. Most patients were male and presented with the disease at a mild bilateral stage in their second decade of life.
摘要:
圆锥角膜的流行病学研究在东南亚有限。对泰国人群圆锥角膜的患病率和特征的研究可以大致了解其影响。
研究屈光手术患者中圆锥角膜的患病率,并分析圆锥角膜的特征。
对2015年4月至2018年8月的病历进行回顾性分析。计算了寻求激光视力矫正的患者中圆锥角膜和圆锥角膜的可疑患病率。本文对圆锥角膜患者的特点进行了综述。Amsler-Krumeich分类用于确定阶段。从地形上看,锥体的类型分为椭圆形,乳头,透明样边缘变性(PMD)样,和散光类型。
圆锥角膜和圆锥角膜可疑患病率分别为1.66%和0.68%,分别。在受影响的患者中,73.8%为男性。诊断时的平均年龄为25.25±8.35岁。目前的症状是视力模糊(87%)和瘙痒(47%)。第一阶段占主导地位,在39%的患者中发现(其次是第2、4和3阶段,分别)。眼部发现包括Munson体征(14.63%),Rizutti标志(6.94%),弗莱舍环(28.14%),Vogt条纹(24.95%),角膜瘢痕(8.63%),角膜神经突出(2.81%),和角膜染色(7.69%)。平均未矫正视力(最小分辨率角度的对数[logMAR])为0.88±0.64。平均矫正视力(logMAR)为0.40±0.49。平均Q值为-0.92±0.63。最薄的厚度为459.39±56.96微米。平均角膜曲率为49.7±6.64屈光度。从地形上看,锥体的类型是椭圆形(57%),散光(33%),PMD样(5%),和乳头类型(4%)。
接受屈光手术的泰国患者中圆锥角膜的患病率为1.66%。大多数患者是男性,在其生命的第二个十年中处于轻度的双侧阶段。
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