OBJECTIVE: We aimed to investigate the clinical characteristics of PFPT in Korean patients.
METHODS: Patients diagnosed with PFPT between 1995 and 2021 at the Pusan National University Hospital were included. Clinical characteristics of PFPT, dermoscopic findings, and comorbidities were reviewed.
RESULTS: A total of 19 patients diagnosed with PFPT were enrolled. The male to female ratio was approximately 1:5. The mean age at diagnosis was 41.1 years (range, 8~67 years). According to Holzwanger\'s classification, Type I was the most common (89.5%). PFPT was commonly concomitant with pigmentary disorders, including mucosal melanotic macules, Laugier-Hunziker syndrome, melasma, and melanonychia (6/19, 31.6%). Preceding oral infection or inflammatory lesions were found in four patients (21.1%), and systemic diseases and infectious diseases existed in two patients (10.5%). Dermoscopic examination was performed in seven patients; pigmented border with dichotomized vessels (rose petal pattern, 71.4%) and diffuse pigmentation (cobblestone pattern, 71.4%) were common findings.
CONCLUSIONS: Our study shows PFPT can coexist with pigmentary disorders. Concomitant pigmentary disorder shows an association with sex hormone or susceptibility to abnormal pigmentation may be a possible cause of PFPT.
目的:我们旨在研究韩国患者PFPT的临床特征。
方法:纳入1995年至2021年在釜山国立大学医院诊断为PFPT的患者。PFPT的临床特点,皮肤镜发现,并对合并症进行了审查。
结果:共纳入19例诊断为PFPT的患者。男女比例约为1:5。诊断时的平均年龄为41.1岁(范围,8~67年)。根据Holzwanger的分类,I型是最常见的(89.5%)。PFPT通常伴有色素性疾病,包括粘膜黑色素斑,Laugier-Hunziker综合征,黄褐斑,和黑甲(6/19,31.6%)。在4例患者中发现了口腔感染或炎性病变(21.1%),2例(10.5%)患者存在全身性疾病和感染性疾病。对7例患者进行了皮肤镜检查;带有二分血管的色素性边界(玫瑰花瓣型,71.4%)和弥漫性色素沉着(鹅卵石图案,71.4%)是常见发现。
结论:我们的研究表明PFPT可以与色素性疾病共存。伴随的色素性疾病显示与性激素有关,或对异常色素沉着的易感性可能是PFPT的可能原因。