Abstract：
Nanomedicine and nano-delivery systems hold unlimited potential in the developing sciences, where nanoscale carriers are employed to efficiently deliver therapeutic drugs at specifically targeted sites in a controlled manner, imparting several advantages concerning improved efficacy and minimizing adverse drug reactions. These nano-delivery systems target-oriented delivery of drugs with precision at several site-specific, with mild toxicity, prolonged circulation time, high solubility, and long retention time in the biological system, which circumvent the problems associated with the conventional delivery approach. Recently, nanocarriers such as dendrimers, liposomes, nanotubes, and nanoparticles have been extensively investigated through structural characteristics, size manipulation, and selective diagnosis through disease imaging molecules, which are very effective and introduce a new paradigm shift in drugs. In this review, the use of nanomedicines in drug delivery has been demonstrated in treating various diseases with significant advances and applications in different fields. In addition, this review discusses the current challenges and future directions for research in these promising fields as well.
摘要：
纳米医学和纳米递送系统在发展科学中具有无限潜力，其中纳米级载体用于以受控方式在特定靶向部位有效地递送治疗药物，赋予关于提高疗效和最小化药物不良反应的几个优点。这些纳米递送系统靶向药物的精确递送在几个特定的位置，具有轻度毒性，延长循环时间，溶解度高,在生命系统中的保留时间很长，这规避了与传统递送方法相关的问题。最近,纳米载体，如树枝状聚合物，脂质体，纳米管,纳米粒子已经通过结构特征进行了广泛的研究，大小操纵，通过疾病成像分子进行选择性诊断，非常有效，并引入了药物的新范式转变。在这次审查中,纳米药物在药物递送中的应用已被证明在治疗各种疾病中具有显著的进展和在不同领域的应用。此外,这篇综述还讨论了这些有前途的领域当前的挑战和未来的研究方向。
