PDF(Pubmed)
Abstract：
Hyperostosis of the skull is a rare bone dysplasia described in disorders such as hyperostosis cranialis interna (HCI) and hyperostosis frontalis interna (HFI). Other syndromes presenting with hyperostosis include Morgagni-Stewart-Morel (MSM) and Troell-Junet. HCI is an abnormal hyperostosis of most endosteal skull and calvarium surface regions. A more specific hyperostosis, HFI, is an unusual bone growth based on its volume and porosity; it is primarily located bilaterally on the frontal portions of the calvarium. However, the hyperossification does not cross the superior sagittal sinus. Upon cadaveric dissection, we found hyperossification beyond the frontal area, extending to the parietal and occipital bones with the significant characteristic of no midline interference. Hyperossification results in gross indentations on the corresponding frontal, parietal, and occipital hemispheric brain tissues. This report discusses possible differentials for this rare cadaveric finding of frontal, parietal, and occipital bone hyperostosis. This case report includes some major characteristic features indicative of HCI and HFI with some interesting variations and features suggestive of MSM and Troell-Junet syndromes. Due to the lack of patient history and medical records, no further conclusions about clinical differentials, symptoms, or causative syndromes could be drawn; further research needs to be conducted on HCI, HFI, and related syndromes to understand their presentations better.
摘要：
颅骨肥大是一种罕见的骨发育不良，在诸如颅骨肥大（HCI）和额骨肥大（HFI）等疾病中描述。其他表现为骨增生的综合征包括Morgagni-Stewart-Morel（MSM）和Troell-Junet。HCI是大多数内骨颅骨和颅骨表面区域的异常增生。更具体的骨肥大，HFI,是基于其体积和孔隙率的不寻常的骨骼生长；它主要位于颅骨的两侧。然而,过度骨化不穿过上矢状窦。尸体解剖后，我们发现额叶区域过度骨化,延伸到顶骨和枕骨，具有无中线干扰的显着特征。过度骨化导致相应额叶上的巨大凹痕，顶叶,和枕骨半球脑组织。本报告讨论了这种罕见的额叶尸体发现的可能差异，顶叶,和枕骨骨肥厚症。该病例报告包括表明HCI和HFI的一些主要特征，以及一些有趣的变化和提示MSM和Troell-Junet综合征的特征。由于缺乏病史和医疗记录，没有关于临床差异的进一步结论，症状,或病因综合征可以得出；需要对HCI、HFI、和相关的综合症，以更好地理解他们的陈述。
