关键词: CABG graft patency saphenous vein

Mesh : Humans Saphenous Vein / transplantation Coronary Artery Bypass / adverse effects methods Atherosclerosis Vascular Patency Treatment Outcome

来  源:   DOI:10.1080/14779072.2023.2233420

Abstract:
UNASSIGNED: The saphenous vein graft (SVG) is the most used conduit in CABG. With standardization of its use as a conduit came an understanding of its accelerated atherosclerosis, known as saphenous vein graft disease (SVGD). Given its extensive use, a review of the pathophysiology and management of SVGD is important as we optimize its use.
UNASSIGNED: For this review, an extensive literature search was completed to identify and examine the evolution of SVG in CABG, mechanisms driving SVGD, and methods developed to prevent and manage it. This includes a review of relevant major papers and trials in this space.
UNASSIGNED: Eras of evolution in SVG usage in CABG include an experimental era, era of SVG dominance in CABG, and the current era of mixed venous and arterial grafting. As SVGD was studied, the mechanisms behind it became more understood, and prevention and management methods were developed. As advances in surgical techniques and pharmacotherapy continue to reduce occurrence and severity of SVGD, long-term patency of SV grafts continues to improve and remain excellent in optimized settings. With continued innovation and improvement in operative techniques, the SVG conduit is and will remain an important player in the field of coronary bypass.
摘要:
隐静脉移植物(SVG)是CABG中最常用的导管。随着其作为导管使用的标准化,人们对其加速的动脉粥样硬化有了了解,称为隐静脉移植物病(SVGD)。鉴于其广泛使用,在我们优化SVGD的使用时,对SVGD的病理生理学和管理进行综述非常重要.
对于这篇评论,完成了广泛的文献检索,以识别和检查CABG中SVG的演变,驱动SVGD的机构,以及预防和管理它的方法。这包括对这一领域相关主要论文和试验的回顾。
CABG中SVG使用的演变过程包括实验时代,SVG在CABG中占主导地位的时代,以及目前静脉和动脉混合移植的时代。随着SVGD的研究,它背后的机制变得更加理解,并制定了预防和管理方法。随着外科技术和药物治疗的进步不断减少SVGD的发生和严重程度,SV移植物的长期通畅性持续改善,并在优化的环境中保持优异.随着手术技术的不断创新和改进,SVG导管是并将继续是冠状动脉搭桥领域的重要参与者。
公众号