PDF(Pubmed)
Abstract：
Blood analysis is a ubiquitous and critical aspect of modern medicine. Analyzing blood samples requires invasive techniques, various testing systems, and samples are limited to relatively small volumes. Photoacoustic imaging (PAI) is a novel imaging modality that utilizes non-ionizing energy that shows promise as an alternative to current methods. This paper seeks to review current applications of PAI in blood analysis for clinical use. Furthermore, we discuss obstacles to implementation and future directions to overcome these challenges. Firstly, we discuss three applications to cellular analysis of blood: sickle cell, bacteria, and circulating tumor cell detection. We then discuss applications to the analysis of blood plasma, including glucose detection and anticoagulation quantification. As such, we hope this article will serve as inspiration for PAI\'s potential application in blood analysis and prompt further studies to ultimately implement PAI into clinical practice.
摘要：
血液分析是现代医学中普遍存在的重要方面。分析血液样本需要侵入性技术，各种测试系统，和样品被限制在相对小的体积。光声成像（PAI）是一种新颖的成像模式，利用非电离能量，有望替代当前的方法。本文旨在回顾PAI在临床血液分析中的当前应用。此外，我们讨论实施的障碍和克服这些挑战的未来方向。首先,我们讨论了血液细胞分析的三个应用：镰状细胞，细菌,和循环肿瘤细胞检测。然后我们讨论血浆分析的应用，包括葡萄糖检测和抗凝定量。因此，我们希望本文能够为PAI在血液分析中的潜在应用提供启发，并促进进一步的研究，最终将PAI应用于临床实践。
